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IRWDIronwood Pharmaceuticals, Inc.
$4.47$736M
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IRWD logoIronwood Pharmaceuticals, Inc.(IRWD)Earnings, Financials & Key Ratios

IRWD•NASDAQ
$4.47
29.8× P/E·Price updated Jul 7, 2026
SectorHealthcareIndustrySpecialty & Generic PharmaSub-IndustryTherapy-focused branded biopharma
AboutIronwood Pharmaceuticals, Inc., a healthcare company, focuses on the development and commercialization of gastrointestinal (GI) products. It markets linaclotide, a guanylate cyclase type-C agonist for the treatment of adults suffering from irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC) under the LINZESS name in the United States and Mexico, as well as under the CONSTELLA name in the Canada and European Union. The company is also developing IW-3300, a GC-C agonist for the treatment of visceral pain conditions, including interstitial cystitis/bladder pain syndrome and endometriosis; and CNP-104, an immune nanoparticle for the treatment of biliary cholangitis. The company has strategic partnerships with AbbVie Inc., AstraZeneca AB, and Astellas Pharma Inc. for the development and commercialization of linaclotide. The company was formerly known as Microbia, Inc. and changed its name to Ironwood Pharmaceuticals, Inc. in April 2008. Ironwood Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Boston, Massachusetts.Show more
  • Revenue$296M-15.7%
  • EBITDA$121M+26.8%
  • Net Income$24M+2629.2%
  • EPS (Diluted)0.15+2627.3%
  • Gross Margin100%+2.2%
  • EBITDA Margin40.74%+50.5%
  • Operating Margin40.1%+51.3%
  • Net Margin8.11%+3138.7%

IRWD Price & Volume

Ironwood Pharmaceuticals, Inc. (IRWD) stock price & volume — 10-year historical chart

Loading chart...

Collaboration Accounting Masks Underlying Operational Revenue Volatility

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Moderate
Financial:Vulnerable
Cash Flow:Mixed
Primary Risk:Single-product revenue concentration

Key Thesis Takeaways

  • Ironwood Pharmaceuticals presents a complex investment profile defined by extreme revenue volatility, as evidenced by the 158.9% year-over-year growth in 2026Q1 following a 47.3% contraction in 2025Q4.
  • While the company maintains high gross margins near 99.6%, its reliance on a single-product collaboration model creates significant earnings instability and necessitates constant monitoring of partner-driven cash flows.
  • Investors should remain cautious regarding the firm's long-term solvency, given the persistent negative equity position of $217.1 million and a substantial debt load of $597.4 million as of 2026Q1.

Verdict Logic

the company's reliance on a single-product collaboration model and its precarious balance sheet, highlighted by a negative equity position of $217.1 million, present excessive risks for long-term capital appreciation.

IRWD Growth Metrics

Ironwood Pharmaceuticals, Inc. (IRWD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years7.07%
5 Years-5.33%
3 Years-10.32%
TTM13.8%

Profit CAGR

10 Years-
5 Years-25.72%
3 Years-48.42%
TTM415.9%

EPS CAGR

10 Years-
5 Years-25.65%
3 Years-46.14%
TTM400.86%

Return on Capital

10 Years-1.74%
5 Years-1.12%
3 Years-20.42%
Last Year50.89%

IRWD Recent Earnings

Ironwood Pharmaceuticals, Inc. (IRWD) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.24+242.9%
$0.07
Rev
$107M+15.6%
$92M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.01-150.0%
$0.02
Rev
$48M-6.3%
$51M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.24+166.7%
$0.09
Rev
$122M+139.6%
$51M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.14+800.0%
$0.02
Rev
$85M+9.5%
$78M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.24vs $0.07+242.9%
$107Mvs $92M+15.6%
Q1 2026Feb 25, 2026
$0.01vs $0.02-150.0%
$48Mvs $51M-6.3%
Q4 2025Nov 10, 2025
$0.24vs $0.09+166.7%
$122Mvs $51M+139.6%
Q3 2025Aug 7, 2025
$0.14vs $0.02+800.0%
$85Mvs $78M+9.5%
Based on last 12 quarters of dataView full earnings history →

Latest IRWD News

Recent stock market news and headlines for Ironwood Pharmaceuticals, Inc. (IRWD)

Zacks Investment Research·Jun 26, 2026
Zacks Industry Outlook Indivior, Aurinia, Ironwood, Altimmune and Marker

Indivior, Aurinia, Ironwood, Altimmune and Marker have been highlighted in this Industry Outlook article.

Zacks Investment Research·Jun 25, 2026
5 Small Drug Stocks to Invest in Amid a Biotech Comeback

Innovation is at its peak in the Zacks Medical-Drugs industry. INDV, AUPH, IRWD, ALT and MRKR may prove to be good additions to one's portfolio.

Peers Comparison

Key metrics vs top competitors for Ironwood Pharmaceuticals, Inc. (IRWD)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
IRWD logoIRWDIronwood Pharmaceuticals, Inc.Current
$4.47$735.82M29.80-15.72%8.11%——
PTGX logoPTGXProtagonist Therapeutics, Inc.
$140.85$9.06B-68.71-89.41%-648.27%-17.76%—
ARDX logoARDXArdelyx, Inc.
$5.38$1.32B-20.6922.09%-13.58%-38.11%—
CPIX logoCPIXCumberland Pharmaceuticals Inc.
$6.29$94.24M-33.1117.57%-17.24%-29.12%—
SUPN logoSUPNSupernus Pharmaceuticals, Inc.
$47.41$2.73B-69.728.63%-3.74%-2.73%—
PRGO logoPRGOPerrigo Company plc
$11.19$1.55B-1.09-2.75%-43.5%-50.65%—

Compare IRWD vs Peers

Ironwood Pharmaceuticals, Inc. (IRWD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PTGX

Most directly comparable listed peer for IRWD.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare IRWD against a more recognizable public peer.

Peer Set

Compare Top 5

vs PTGX, ARDX, CPIX, SUPN

IRWD SEC Filings & Documents

Ironwood Pharmaceuticals, Inc. (IRWD) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

May 7, 2026·SEC

Material company update

Mar 11, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Feb 16, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 11, 2025·SEC

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IRWD Frequently Asked Questions

Ironwood Pharmaceuticals, Inc. (IRWD) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Ironwood Pharmaceuticals, Inc.'s revenue?

Ironwood Pharmaceuticals, Inc. (IRWD) reported $361.5M in revenue for fiscal year 2025. This represents a 3355% increase from $10.5M in 2007.

How fast is Ironwood Pharmaceuticals, Inc. growing?

Ironwood Pharmaceuticals, Inc. (IRWD) saw revenue decline by 15.7% over the past year.

Is IRWD profitable?

Yes, Ironwood Pharmaceuticals, Inc. (IRWD) is profitable, generating $102.2M in net income for fiscal year 2025 (8.1% net margin).

Dividend & Returns
What is Ironwood Pharmaceuticals, Inc.'s free cash flow?

Ironwood Pharmaceuticals, Inc. (IRWD) generated $112.2M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in IRWD back in 2007?

Total return calculator · dividends reinvested · 19+ years of data

See returns →