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GUTSFractyl Health, Inc. Common Stock
$0.76$55M
Overview & Verdict
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GUTS logoFractyl Health, Inc. Common Stock(GUTS)Earnings, Financials & Key Ratios

GUTS•NASDAQ
$0.78
Price updated Jul 2, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutFractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. The company develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans. It also develops Rejuva, a novel virus delivered pancreatic gene therapy platform that is designed to enable long-term remission of T2D and obesity by durably altering metabolic hormone function in the pancreatic islet cells of patients. Fractyl Health, Inc. was formerly known as Fractyl Laboratories Inc. and changed its name to Fractyl Health, Inc. on June 09, 2021. The company was incorporated in 2010 and is based in Lexington, Massachusetts.Show more
  • Revenue$0-100.0%
  • EBITDA-$96M-3.1%
  • Net Income-$141M-105.2%
  • EPS (Diluted)-1.86-14.8%
  • ROE-744.17%-207.9%

GUTS Price & Volume

Fractyl Health, Inc. Common Stock (GUTS) stock price & volume — 10-year historical chart

Loading chart...

Clinical Development Costs Outpace Revenue Generation Potential

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding dependency

Key Thesis Takeaways

  • Fractyl Health operates as a high-risk, pre-revenue entity heavily dependent on external financing to sustain its Revita system development.
  • While the company reported a $9.2 million net income in 2026Q1, this figure appears decoupled from operational reality given the persistent quarterly cash burn exceeding $20 million.
  • Investors should monitor the company's ability to reach commercial scale before its $63.2 million cash position is exhausted by ongoing R&D requirements.

Verdict Logic

the company's reliance on external financing is highlighted by a consistent quarterly cash burn that has reduced the total asset base from $163.5 million in 2024Q1 to $99.4 million by 2026Q1.

GUTS Growth Metrics

Fractyl Health, Inc. Common Stock (GUTS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-100%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-21.2%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM5.43%

Return on Capital

10 Years-170.55%
5 Years-91.05%
3 Years-102.95%
Last Year-101.18%

GUTS Recent Earnings

Fractyl Health, Inc. Common Stock (GUTS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (40%)●Beat Revenue 0/12 qtrs (0%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.06+135.3%
$0.17
Rev
—
—
Q2 2026
Mar 24, 2026
Metric
Actual
Est
EPS
$0.15+178.9%
$0.19
Rev
—
—
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.35-2.9%
$0.34
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.53-43.2%
$0.37
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.06vs $0.17+135.3%
—
Q2 2026Mar 24, 2026
$0.15vs $0.19+178.9%
—
Q4 2025Nov 12, 2025
$0.35vs $0.34-2.9%
—
Q3 2025Aug 12, 2025
$0.53vs $0.37-43.2%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Fractyl Health, Inc. Common Stock (GUTS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
GUTS logoGUTSFractyl Health, Inc. Common StockCurrent
$0.78$56.49M-0.42-100%—-744.17%—
NVAX logoNVAXNovavax, Inc.
$9.46$1.56B3.7264.69%-14.73%——
ELVN logoELVNEnliven Therapeutics, Inc.
$48.76$2.97B-26.64——-21.04%—
RNAC logoRNACCartesian Therapeutics, Inc.
$10.18$299.1M-2.03-92.81%-8550.65%——
RMTI logoRMTIRockwell Medical, Inc.
$5.19$20.49M-3.46-31.76%-7.98%-15.41%—
DNLI logoDNLIDenali Therapeutics Inc.
$25.98$4.12B-8.75——-52.2%—

Compare GUTS vs Peers

Fractyl Health, Inc. Common Stock (GUTS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NVAX

Most directly comparable listed peer for GUTS.

Scale Benchmark

vs LLY

Larger-name benchmark to compare GUTS against a more recognizable public peer.

Peer Set

Compare Top 5

vs NVAX, ELVN, RNAC, RMTI

GUTS SEC Filings & Documents

Fractyl Health, Inc. Common Stock (GUTS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

May 11, 2026·SEC

Material company update

Mar 24, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 24, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Apr 1, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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GUTS Frequently Asked Questions

Fractyl Health, Inc. Common Stock (GUTS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
How fast is Fractyl Health, Inc. Common Stock growing?

Fractyl Health, Inc. Common Stock (GUTS) saw revenue decline by 100.0% over the past year.

Is GUTS profitable?

Fractyl Health, Inc. Common Stock (GUTS) reported a net loss of $108.0M for fiscal year 2025.

Dividend & Returns
What is GUTS's return on equity?

Fractyl Health, Inc. Common Stock (GUTS) has a return on equity (ROE) of -744.2%. Negative ROE indicates the company is unprofitable.

What is Fractyl Health, Inc. Common Stock's free cash flow?

Fractyl Health, Inc. Common Stock (GUTS) had negative free cash flow of $87.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in GUTS back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →