Edgewise Therapeutics, Inc. (EWTX) Discusses Top Line Data From EDG-7500 Phase II CIRRUS-HCM Trial in Hypertrophic Cardiomyopathy Transcript

Edgewise Therapeutics, Inc. (EWTX) stock price & volume — 10-year historical chart
Investment Thesis • Updated 2026Q1
the company's persistent free cash flow deficit of $42.8 million in 2026Q1 and the rapid depletion of cash reserves to $33.2 million present substantial execution risks for long-term investors.
Edgewise Therapeutics, Inc. (EWTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Edgewise Therapeutics, Inc. (EWTX) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | May 7, 2026 | $0.46vs $0.50+8.0% | — |
| Q1 2026 | Feb 26, 2026 | $0.47vs $0.43-9.3% | — |
| Q4 2025 | Nov 6, 2025 | $0.39vs $0.40+2.5% | — |
| Q3 2025 | Aug 7, 2025 | $0.34vs $0.42+19.0% | — |
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Edgewise Therapeutics, Inc. (EWTX) Discusses Top Line Data From EDG-7500 Phase II CIRRUS-HCM Trial in Hypertrophic Cardiomyopathy Transcript

Edgewise Therapeutics Inc. (NASDAQ:EWTX) on Tuesday released topline results from the 12-week Part D cohort of its Phase 2 CIRRUS-HCM trial.

Edgewise Therapeutics shares fell nearly 10% on Tuesday after the efficacy of its experimental heart-disease drug in a mid-stage study fell short of investor expectations.

– No relationship observed between EDG-7500 exposure and LVEF; no LVEF reductions below 50% – – Consistent and clinically meaningful improvements observed in echocardiogram parameters, biomarkers, symptoms and functional status across obstructive and nonobstructive HCM – – EDG-7500 administration continued to be generally well tolerated – – Company to host webcast today at 8:30 a.m. Eastern Time – BOULDER, Colo.

Key metrics vs top competitors for Edgewise Therapeutics, Inc. (EWTX)
| Company | Price | Market Cap | P/E Ratio | Rev Growth (1Y) | Net Margin | ROE | Div Yield |
|---|---|---|---|---|---|---|---|
| $39.15 | $4.21B | -24.02 | — | — | -34.19% | — | |
| $25.20 | $4.31B | 11.00 | 11.87% | 34.3% | 35.65% | — | |
| $114.20 | $9.32B | -30.95 | -16.72% | -612.17% | -25.02% | — | |
| $13.29 | $1.28B | -4.31 | — | — | -151.02% | — | |
| $38.14 | $7.83B | -13.77 | — | — | -68.16% | — | |
| $25.84 | $3.23B | -198.77 | 91.34% | -0.57% | -1.41% | — |
Edgewise Therapeutics, Inc. (EWTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Edgewise Therapeutics, Inc. (EWTX) SEC filings — annual & quarterly reports (10-K, 10-Q)
May 7, 2026·SEC
Feb 26, 2026·SEC
Nov 20, 2025·SEC
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Edgewise Therapeutics, Inc. (EWTX) stock FAQ — growth, dividends, profitability & financials explained
Edgewise Therapeutics, Inc. (EWTX) reported a net loss of $176.0M for fiscal year 2025.
Edgewise Therapeutics, Inc. (EWTX) has a return on equity (ROE) of -34.2%. Negative ROE indicates the company is unprofitable.
Edgewise Therapeutics, Inc. (EWTX) had negative free cash flow of $148.7M in fiscal year 2025, likely due to heavy capital investments.