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EWTXEdgewise Therapeutics, Inc.
$39.56$4.3B
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EWTX logoEdgewise Therapeutics, Inc.(EWTX)Earnings, Financials & Key Ratios

EWTX•NASDAQ
$39.15
Price updated Jul 2, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutEdgewise Therapeutics, Inc., a biopharmaceutical company, develops small molecule therapies for musculoskeletal diseases. The Company's lead product candidate, EDG-5506, is an orally administered small molecule designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy which has completed Phase 1 clinical trial. It develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. Edgewise Therapeutics, Inc. was incorporated in 2017 and is headquartered in Boulder, Colorado.Show more
  • Revenue$0
  • EBITDA-$189M-20.8%
  • Net Income-$168M-25.4%
  • EPS (Diluted)-1.63-12.4%
  • ROE-34.19%+0.6%

EWTX Price & Volume

Edgewise Therapeutics, Inc. (EWTX) stock price & volume — 10-year historical chart

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Escalating Clinical R&D Costs Pressure Liquidity Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding dependency

Key Thesis Takeaways

  • Edgewise Therapeutics remains in a high-intensity development phase, characterized by a widening quarterly operating loss that reached $54.1 million in 2026Q1.
  • While the company maintains a clean balance sheet with a 0.01 debt-to-equity ratio, its reliance on equity-funded R&D creates significant structural vulnerability as cash reserves dwindle.
  • Investors should monitor the company's ability to achieve pivotal clinical milestones, as the current burn rate necessitates consistent access to capital markets to sustain operations.

Verdict Logic

the company's persistent free cash flow deficit of $42.8 million in 2026Q1 and the rapid depletion of cash reserves to $33.2 million present substantial execution risks for long-term investors.

EWTX Growth Metrics

Edgewise Therapeutics, Inc. (EWTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-20.48%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-7.1%

Return on Capital

10 Years-31.83%
5 Years-31.51%
3 Years-37.7%
Last Year-38.74%

EWTX Recent Earnings

Edgewise Therapeutics, Inc. (EWTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.46+8.0%
$0.50
Rev
—
—
Q1 2026
Feb 26, 2026
Metric
Actual
Est
EPS
$0.47-9.3%
$0.43
Rev
—
—
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.39+2.5%
$0.40
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.34+19.0%
$0.42
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.46vs $0.50+8.0%
—
Q1 2026Feb 26, 2026
$0.47vs $0.43-9.3%
—
Q4 2025Nov 6, 2025
$0.39vs $0.40+2.5%
—
Q3 2025Aug 7, 2025
$0.34vs $0.42+19.0%
—
Based on last 12 quarters of dataView full earnings history →

Latest EWTX News

Recent stock market news and headlines for Edgewise Therapeutics, Inc. (EWTX)

Seeking Alpha·Jun 17, 2026
Edgewise Therapeutics, Inc. (EWTX) Discusses Top Line Data From EDG-7500 Phase II CIRRUS-HCM Trial in Hypertrophic Cardiomyopathy Transcript

Edgewise Therapeutics, Inc. (EWTX) Discusses Top Line Data From EDG-7500 Phase II CIRRUS-HCM Trial in Hypertrophic Cardiomyopathy Transcript

Benzinga·Jun 16, 2026
Edgewise Therapeutics Reports Improvements In Heart Drug Trial

Edgewise Therapeutics Inc. (NASDAQ:EWTX) on Tuesday released topline results from the 12-week Part D cohort of its Phase 2 CIRRUS-HCM trial.

Reuters·Jun 16, 2026
Edgewise shares slip after heart-disease drug trial data disappoints investors

Edgewise Therapeutics shares fell nearly 10% on Tuesday after the efficacy of its experimental heart-disease drug in a mid-stage study ​fell short of investor expectations.

PRNewsWire·Jun 16, 2026
Edgewise Therapeutics Announces Positive Top-Line Data from 12-Week Phase 2 CIRRUS-HCM Trial with EDG-7500 in Obstructive and Nonobstructive Hypertrophic Cardiomyopathy (HCM)

– No relationship observed between EDG-7500 exposure and LVEF; no LVEF reductions below 50% – – Consistent and clinically meaningful improvements observed in echocardiogram parameters, biomarkers, symptoms and functional status across obstructive and nonobstructive HCM  – – EDG-7500 administration continued to be generally well tolerated – – Company to host webcast today at 8:30 a.m. Eastern Time – BOULDER, Colo.

Peers Comparison

Key metrics vs top competitors for Edgewise Therapeutics, Inc. (EWTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
EWTX logoEWTXEdgewise Therapeutics, Inc.Current
$39.15$4.21B-24.02——-34.19%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.20$4.31B11.0011.87%34.3%35.65%—
KYMR logoKYMRKymera Therapeutics, Inc.
$114.20$9.32B-30.95-16.72%-612.17%-25.02%—
CMPS logoCMPSCOMPASS Pathways plc
$13.29$1.28B-4.31——-151.02%—
IMVT logoIMVTImmunovant, Inc.
$38.14$7.83B-13.77——-68.16%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$25.84$3.23B-198.7791.34%-0.57%-1.41%—

Compare EWTX vs Peers

Edgewise Therapeutics, Inc. (EWTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for EWTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare EWTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, KYMR, CMPS, IMVT

EWTX SEC Filings & Documents

Edgewise Therapeutics, Inc. (EWTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Feb 26, 2026·SEC

Material company update

Nov 20, 2025·SEC

10-K Annual Reports

4
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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EWTX Frequently Asked Questions

Edgewise Therapeutics, Inc. (EWTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is EWTX profitable?

Edgewise Therapeutics, Inc. (EWTX) reported a net loss of $176.0M for fiscal year 2025.

Dividend & Returns
What is EWTX's return on equity?

Edgewise Therapeutics, Inc. (EWTX) has a return on equity (ROE) of -34.2%. Negative ROE indicates the company is unprofitable.

What is Edgewise Therapeutics, Inc.'s free cash flow?

Edgewise Therapeutics, Inc. (EWTX) had negative free cash flow of $148.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in EWTX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →