Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CTMX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 32.0M | $150.2M | +29.4% | 19.870% | 0.01% |
| 2 | Kynam Capital Management, LP | 15.0M | $70.6M | +67.4% | 9.335% | 4.41% |
| 3 | BANK OF AMERICA CORP /DE/ | 10.2M | $48.0M | +1064.3% | 6.344% | 0.00% |
| 4 | PERCEPTIVE ADVISORS LLC | 10.1M | $47.5M | +4.3% | 6.279% | 0.94% |
| 5 | VR Adviser, LLC | 10.0M | $46.9M | -35.9% | 6.207% | 1.75% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 8.7M | $41.0M | β | 5.430% | 0.00% |
| 7 | Point72 Asset Management, L.P. | 7.9M | $37.0M | +51.8% | 4.897% | 0.05% |
| 8 | CITADEL ADVISORS LLC | 5.9M | $27.7M | +1147.7% | 3.668% | 0.01% |
| 9 | STATE STREET CORP | 5.7M | $26.6M | +10.2% | 3.522% | 0.00% |
| 10 | BlackRock, Inc. | 5.2M | $24.6M | +42.5% | 3.251% | 0.00% |
| 11 | BAKER BROS. ADVISORS LP | 5.0M | $23.4M | +17.1% | 3.094% | 0.13% |
| 12 | Elmind Capital, LP | 4.5M | $21.4M | +550.0% | 2.829% | 6.07% |
| 13 | Nextech Invest, Ltd. | 4.4M | $20.9M | β | 2.767% | 1.47% |
| 14 | MARSHALL WACE, LLP | 4.1M | $19.4M | +257.7% | 2.573% | 0.02% |
| 15 | MILLENNIUM MANAGEMENT LLC | 3.7M | $17.2M | +1163.7% | 2.276% | 0.01% |
| 16 | WELLINGTON MANAGEMENT GROUP LLP | 3.6M | $16.8M | β | 2.228% | 0.00% |
| 17 | Siren, L.L.C. | 3.5M | $16.3M | β | 2.150% | 0.45% |
| 18 | ADAR1 Capital Management, LLC | 3.4M | $16.0M | -20.4% | 2.121% | 1.00% |
| 19 | Eversept Partners, LP | 3.2M | $15.0M | +27.2% | 1.983% | 0.98% |
| 20 | UBS Group AG | 3.1M | $14.7M | +741.6% | 1.940% | 0.00% |
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3.1M | $14.5M | +185.2% | 1.915% | 0.00% |
| 22 | Jefferies Financial Group Inc. | 3.1M | $14.4M | +12809.7% | 1.908% | 0.10% |
| 23 | TWO SIGMA INVESTMENTS, LP | 2.7M | $12.7M | +73.6% | 1.685% | 0.01% |
| 24 | Qube Research & Technologies Ltd | 2.2M | $10.6M | +112.0% | 1.399% | 0.01% |
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 2.1M | $9.7M | +35.5% | 1.285% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in CTMX β a direct measure of their conviction.
Filings activity in CTMX during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 173 | +45% | 189.31% | +66.52 pp | $916M | +54% |
| Q4 2025 | 119 | +17% | 122.79% | +35.17 pp | $594M | +40% |
| Q3 2025 | 102 | +23% | 87.62% | +26.04 pp | $424M | +42% |
| Q2 2025 | 83 | +26% | 61.58% | +56.13 pp | $298M | +1029% |
| Q1 2025 | 66 | 5.7% | 5.45% | 3.80 pp | $26M | 41% |
| Q4 2024 | 70 | +4.5% | 9.25% | 2.30 pp | $45M | 20% |
| Q3 2024 | 67 | 8.2% | 11.55% | 0.35 pp | $56M | 3.0% |
| Q2 2024 | 73 | β | 11.90% | β | $58M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CTMX stock.
Based on Q1 2026 13F filings, institutional ownership of CytomX Therapeutics, Inc. stands at 189.3%, held across 173 reporting institutions.
FMR LLC is the largest reported institutional holder of CTMX, with approximately 31,955,637 shares worth $0.15B as of Q1 2026.
Yes β 5 widely-followed marquee investors appear among the top 25 institutional holders of CTMX, including Point72 Asset Management, L.P., CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for CTMX is 89 out of 100 (Strong Smart Money). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
76 institutions opened new positions in CTMX during Q1 2026, while 22 fully exited. 74 added to existing positions and 22 trimmed.
CTMX institutional ownership rose by 66.52 percentage points quarter-over-quarter, with a net change of +54 holders.
The top 10 institutions account for 56.8% of all reported 13F value in CTMX, and the top 25 account for 83.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
CytomX Therapeutics, Inc. (CTMX) Institutional Ownership