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CRSPCRISPR Therapeutics AG
$61.89$6.0B
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CRSP logoCRISPR Therapeutics AG (CRSP) Earnings History

Net Loss

12 years of earnings data (2014–2025) · Currently unprofitable on a TTM basis

TTM Net Income
-$569M
● Net Loss
TTM EPS (Diluted)
$-5.92
Per share, diluted
YoY EPS Growth
-49.1%
Declining
Net Margin
-16569.8%
After-tax profitability
EPS Growth Rate (CAGR)
1YN/A
3YN/A
5YN/A
10YN/A
Operating Margin-16191.4%
Gross Margin-6537.0%
Return on Equity-30.2%
Return on Assets-25.8%
Record Annual Net Income$378MFY2021
Record Quarterly EPS$9.44Q2 2021
Consecutive Profitable Years0years
Q1 2026
Net Income-$123M
EPS (Diluted)$-1.28
YoY Growth-49.1%Declining
QoQ Growth+5.9%Solid

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CRISPR Therapeutics AG (CRSP) Earnings Overview

As of July 7, 2026, CRISPR Therapeutics AG (CRSP) reported trailing twelve-month net income of -$569M, reflecting -49.1% year-over-year growth. The company earned $-5.92 per diluted share over the past four quarters, with a net profit margin of -16569.8%.

Looking at the long-term picture, CRSP's historical earnings data spans multiple years. The company achieved its highest annual net income of $378M in fiscal 2021.

CRISPR Therapeutics AG is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including EDIT (-$109M net income, -395.0% margin), NTLA (-$395M net income, -609.9% margin), BEAM (-$65M net income, -57.2% margin), CRSP has room to improve margins relative to the peer group. Compare CRSP vs EDIT →

CRSP Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
CRSP logoCRSPCurrent
-$569M$-5.92-16569.8%-30.2%-49.1%—
EDIT logoEDIT
-$109M$-1.11-395.0%-198.1%+37.5%
NTLA logoNTLA
-$395M$-3.33-609.9%-53.5%+27.4%
BEAM logoBEAM
-$65M$-0.63-57.2%-8.1%+82.3%
SGMO logoSGMO
-$123M$-0.32-310.8%-2891.8%+10.2%
PRME logoPRME
-$198M$-1.12-4342.4%-146.8%+18.3%
Best in group
Lowest in group

CRSP Historical Earnings Data (2014–2025)

12 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$582M-58.8%-$568M$-6.47-16569.8%-16191.4%
2024-$366M-138.4%-$467M$-4.34-1046.4%-1333.0%
2023-$154M+76.4%-$223M$-1.94-41.5%-60.1%
2022-$650M-272.2%-$673M$-8.36-149122.7%-154394.7%
2021$378M+208.3%$374M$4.7041.4%40.9%
2020-$349M-621.8%-$354M$-5.29-48520.9%-49295.5%
2019$67M+140.5%$47M$1.1723.1%16.1%
2018-$165M-141.4%-$159M$-3.44-5281.1%-5087.8%
2017-$68M-194.6%-$65M$-1.71-166.7%-157.7%
2016-$23M+10.2%-$68M$-1.89-449.3%-1319.3%
2015-$26M-279.8%-$26M$-0.88-10456.7%-10416.6%
2014-$7M--$7M$-0.23--

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CRSP — Frequently Asked Questions

Quick answers to the most common questions about buying CRSP stock.

What is CRSP earnings per share (EPS)?

CRSP trailing twelve-month (TTM) diluted EPS is $-5.92, reflecting -49.1% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2014 to 2025 is available in the table on this page.

What is CRISPR Therapeutics AG's net income?

CRISPR Therapeutics AG (CRSP) trailing twelve-month net income is $-569M as of 2025. Earnings declined -49.1% year-over-year.

Is CRSP profitable?

CRSP is not currently profitable on a TTM basis, reporting a net loss of $-569M. Net margin is -16569.8%. Investors should monitor for a return to profitability.

What is CRSP's earnings growth rate?

CRSP compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2014 to 2025.

What are CRSP's profit margins?

CRISPR Therapeutics AG net profit margin is -16569.8%, operating margin is -16191.4%, and gross margin is -6537.0%. Below-average margins reflect competitive or cost pressures. Return on Equity is -30.2%.

Is CRSP growing earnings?

CRSP earnings are declining — EPS fell -49.1% year-over-year. TTM net income dropped to $-569M. This contrasts with the 5-year CAGR of N/A.

What was CRSP's best earnings year?

CRISPR Therapeutics AG's highest annual net income on record is $378M, achieved in fiscal year 2021. Earnings history on this page spans 2014 to 2025 and includes all annual and quarterly figures.

What were CRSP's earnings last quarter?

CRSP's most recent reported quarter was Q1 2026. Net income was $-123M with diluted EPS of $-1.28. For a full breakdown of all quarters, see the quarterly earnings table on this page.

CRSP Earnings Over Time (2014–2025)

Net income & EPS — annual and quarterly view