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CASICASI Pharmaceuticals, Inc.
$0.15$2M
Overview & Verdict
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CASI logoCASI Pharmaceuticals, Inc.(CASI)Earnings, Financials & Key Ratios

CASI•NASDAQ
$0.15
Price updated Jun 20, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Specialty Pharma
AboutCASI Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes therapeutics and pharmaceutical products in China, the United States, and internationally. It offers EVOMELA, an intravenous formulation of melphalan for use as a conditioning treatment prior to stem cell transplantation, and as a palliative treatment for patients with multiple myeloma. The company's product pipeline includes CNCT19, an autologous CD19 CAR-T investigative product for the treatment of patients with B-cell acute lymphoblastic leukemia (B-ALL) and B-cell non-Hodgkin lymphoma (B-NHL); BI-1206 that is in Phase I/II trial in combination with anti-PD1 therapy Keytruda for solid tumors, and in a Phase I/IIa trial in combination with MabThera (rituximab) in patients with relapsed/refractory NHL; and CB-5339, which is in Phase I clinical trial for acute myeloid leukemia and myelodysplastic syndrome. Its product pipeline also comprises CID-103 for the treatment of patients with multiple myeloma; Thiotepa, which has multiple indications including use as a conditioning treatment for various allogeneic haemopoietic stem cell transplants; and Octreotide long acting injectable formulations for the treatment of acromegaly and for the control of symptoms associated with various neuroendocrine tumors. The company has licensing agreements with Juventas Cell Therapy Ltd; BioInvent International AB; Black Belt Therapeutics Limited; and Cleave Therapeutics, Inc. It also has distribution agreements with China Resources Pharmaceutical Commercial Group International Trading Co., Ltd; Pharmathen Global BV; and Riemser Pharma GmbH. The company was formerly known as EntreMed, Inc. and changed its name to CASI Pharmaceuticals, Inc. in June 2014. CASI Pharmaceuticals, Inc. was incorporated in 1991 and is based in Rockville, Maryland.Show more
  • Revenue$29M-15.8%
  • EBITDA-$37M-74.8%
  • Net Income-$39M-45.7%
  • EPS (Diluted)-2.56-26.7%
  • Gross Margin39.06%-34.0%
  • EBITDA Margin-130.67%-107.5%
  • Operating Margin-138.84%-87.6%
  • Net Margin-137.57%-73.0%
  • ROE-301.8%-410.3%

CASI Price & Volume

CASI Pharmaceuticals, Inc. (CASI) stock price & volume — 10-year historical chart

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Persistent Operating Losses Threaten Corporate Solvency

Investment Thesis • Updated 2025Q3

VerdictNeutral
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and solvency

Key Thesis Takeaways

  • CASI Pharmaceuticals faces a critical inflection point as its commercial model struggles to gain traction in the Chinese oncology market, evidenced by a 60.5% year-over-year revenue decline in 2025Q3.
  • The company's reliance on in-licensed assets has failed to generate positive free cash flow, leading to a precarious liquidity position characterized by a current ratio of 0.30.
  • Investors should monitor the firm's ability to address its negative equity of $28.6 million, as the current trajectory suggests significant risk of further capital dilution or operational insolvency.

Verdict Logic

Negative: The company's current ratio of 0.30 and persistent operating losses of $10.7 million in 2025Q3 indicate severe liquidity constraints that outweigh potential upside.

CASI Growth Metrics

CASI Pharmaceuticals, Inc. (CASI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years103.24%
5 Years47.19%
3 Years-1.84%
TTM21.72%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-59.58%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-41.7%

Return on Capital

10 Years-20.22%
5 Years-50.01%
3 Years-55.64%
Last Year-104.59%

Peers Comparison

Key metrics vs top competitors for CASI Pharmaceuticals, Inc. (CASI)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CASI logoCASICASI Pharmaceuticals, Inc.Current
$0.15$2.33M-0.06-15.77%-137.57%-301.8%31.1%
ZLAB logoZLABZai Lab Limited
$19.08$2.11B-11.9315.33%-39.29%-24.32%—
LEGN logoLEGNLegend Biotech Corporation
$28.04$5.19B-17.5364.04%-21.97%-24.91%—
ZYME logoZYMEZymeworks Inc.
$25.33$1.86B-23.4538.87%-126.33%-0.25%—
CAN logoCANCanaan Inc.
$0.29$184M-0.6496.69%-39.68%-60.72%—
HALO logoHALOHalozyme Therapeutics, Inc.
$80.78$9.58B31.5537.55%23.13%126.27%—

Compare CASI vs Peers

CASI Pharmaceuticals, Inc. (CASI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ZLAB

Most directly comparable listed peer for CASI.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare CASI against a more recognizable public peer.

Peer Set

Compare Top 5

vs ZLAB, LEGN, ZYME, CAN

CASI SEC Filings & Documents

CASI Pharmaceuticals, Inc. (CASI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 21, 2023·SEC

Material company update

Jan 31, 2023·SEC

Material company update

Nov 14, 2022·SEC

10-K Annual Reports

1
FY 2022

Mar 28, 2022·SEC

10-Q Quarterly Reports

4
FY 2022

Nov 14, 2022·SEC

FY 2022

Aug 12, 2022·SEC

FY 2022

May 12, 2022·SEC

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CASI Frequently Asked Questions

CASI Pharmaceuticals, Inc. (CASI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is CASI Pharmaceuticals, Inc.'s revenue?

CASI Pharmaceuticals, Inc. (CASI) reported $26.8M in revenue for fiscal year 2024. This represents a 3629% increase from $0.7M in 1995.

How fast is CASI Pharmaceuticals, Inc. growing?

CASI Pharmaceuticals, Inc. (CASI) saw revenue decline by 15.8% over the past year.

Is CASI profitable?

CASI Pharmaceuticals, Inc. (CASI) reported a net loss of $49.4M for fiscal year 2024.

Dividend & Returns
Does CASI pay dividends?

Yes, CASI Pharmaceuticals, Inc. (CASI) pays a dividend with a yield of 31.10%. This makes it attractive for income-focused investors.

What is CASI's return on equity?

CASI Pharmaceuticals, Inc. (CASI) has a return on equity (ROE) of -301.8%. Negative ROE indicates the company is unprofitable.

What is CASI Pharmaceuticals, Inc.'s free cash flow?

CASI Pharmaceuticals, Inc. (CASI) had negative free cash flow of $29.5M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in CASI back in 1995?

Total return calculator · dividends reinvested · 31+ years of data

See returns →