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AYTUAytu BioPharma, Inc.
$2.25$18M
Overview & Verdict
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AYTU logoAytu BioPharma, Inc.(AYTU)Earnings, Financials & Key Ratios

AYTU•NASDAQ
$2.25
Price updated Jul 7, 2026
SectorHealthcareIndustrySpecialty & Generic PharmaSub-IndustrySpecialty pharma brand consolidators
AboutAytu Biopharma, Inc., a specialty pharmaceutical company, focuses on developing and commercializing novel therapeutics and consumer healthcare products the United States and internationally. The company offers Adzenys XR-ODT for the treatment of attention deficit hyperactivity disorder (ADHD) in patients from 6 years and older; Cotempla XR-ODT for the treatment of ADHD in patients from 6 to 17 years old; and Adzenys ER, an oral suspension for the treatment of ADHD in patients from 6 years and older. It also provides Karbinal ER, a carbinoxamine oral suspension for the treatment of seasonal and perennial allergies; Poly-Vi-Flor and Tri-Vi-Flor prescription supplements for infants and children for the treatment of fluoride deficiency; Tuzistra XR, a prescription antitussive consisting of codeine polistirex and chlorpheniramine polistirex in an oral suspension; and ZolpiMist, an oral spray for the treatment of insomnia. The company was formerly known as Aytu BioScience, Inc. and changed its name to Aytu Biopharma, Inc. in March 2021. Aytu Biopharma, Inc. was incorporated in 2015 and is headquartered in Englewood, Colorado.Show more
  • Revenue$66M+1.8%
  • EBITDA-$2M-147.7%
  • Net Income-$14M+14.4%
  • EPS (Diluted)-2.16+24.5%
  • Gross Margin69.04%-8.3%
  • EBITDA Margin-3.69%-146.9%
  • Operating Margin-11.79%-383.1%
  • Net Margin-20.43%+15.9%
  • ROE-58.1%-23.0%

AYTU Price & Volume

Aytu BioPharma, Inc. (AYTU) stock price & volume — 10-year historical chart

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Persistent Revenue Contraction Challenges Operational Viability

Investment Thesis • Updated 2026Q3

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Persistent operating cash burn

Key Thesis Takeaways

  • Aytu BioPharma faces a challenging outlook as its core ADHD and specialty portfolio struggles to maintain market share, evidenced by a revenue decline to $12.4M in 2026Q3 from $18.7M in 2024Q2.
  • The company's inability to achieve operating scale, highlighted by a -32.7% operating margin in 2026Q3, suggests that its current cost structure remains misaligned with its commercial output.
  • Investors should monitor the company's reliance on a $42.5M goodwill balance, which represents 38% of total assets, as persistent operating losses may necessitate future impairment charges.

Verdict Logic

the company's inability to generate consistent operating cash flow, combined with a net margin of -45.3% in 2026Q3, suggests significant ongoing risk to shareholder equity.

AYTU Growth Metrics

Aytu BioPharma, Inc. (AYTU) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years73.94%
5 Years19.16%
3 Years-11.78%
TTM-18.24%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-2177.79%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-535.74%

Return on Capital

10 Years-70.95%
5 Years-35.52%
3 Years-13.29%
Last Year-13.3%

AYTU Recent Earnings

Aytu BioPharma, Inc. (AYTU) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.53-19.5%
$0.44
Rev
$12M+3.0%
$12M
Q1 2026
Feb 3, 2026
Metric
Actual
Est
EPS
$1.05-303.8%
$0.26
Rev
$15M+24.9%
$12M
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.08-33.3%
$0.06
Rev
$14M+10.2%
$13M
Q4 2025
Sep 23, 2025
Metric
Actual
Est
EPS
$0.26-1200.0%
$0.02
Rev
$15M-15.5%
$18M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.53vs $0.44-19.5%
$12Mvs $12M+3.0%
Q1 2026Feb 3, 2026
$1.05vs $0.26-303.8%
$15Mvs $12M+24.9%
Q4 2025Nov 13, 2025
$0.08vs $0.06-33.3%
$14Mvs $13M+10.2%
Q4 2025Sep 23, 2025
$0.26vs $0.02-1200.0%
$15Mvs $18M-15.5%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Aytu BioPharma, Inc. (AYTU)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AYTU logoAYTUAytu BioPharma, Inc.Current
$2.25$18.22M-1.041.84%-20.43%-58.1%—
SUPN logoSUPNSupernus Pharmaceuticals, Inc.
$47.41$2.73B-69.728.63%-3.74%-2.73%—
TPVG logoTPVGTriplePoint Venture Growth BDC Corp.
$4.75$192.85M3.8936.55%-19.55%-3.39%—
ASRT logoASRTAssertio Holdings, Inc.
$23.50$151.86M-4.96-5%-34.94%-38.72%—
PRGO logoPRGOPerrigo Company plc
$11.19$1.55B-1.09-2.75%-43.5%-50.65%—
COLL logoCOLLCollegium Pharmaceutical, Inc.
$36.44$1.18B21.0623.62%9.41%26.74%—

Compare AYTU vs Peers

Aytu BioPharma, Inc. (AYTU) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SUPN

Most directly comparable listed peer for AYTU.

Scale Benchmark

vs CVS

Larger-name benchmark to compare AYTU against a more recognizable public peer.

Peer Set

Compare Top 5

vs SUPN, TPVG, ASRT, PRGO

AYTU SEC Filings & Documents

Aytu BioPharma, Inc. (AYTU) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

Apr 2, 2026·SEC

Material company update

Feb 3, 2026·SEC

10-K Annual Reports

3
FY 2025

Sep 23, 2025·SEC

FY 2024

Sep 26, 2024·SEC

FY 2023

Oct 12, 2023·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2026

Feb 3, 2026·SEC

FY 2025

Nov 13, 2025·SEC

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AYTU Frequently Asked Questions

Aytu BioPharma, Inc. (AYTU) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Aytu BioPharma, Inc.'s revenue?

Aytu BioPharma, Inc. (AYTU) reported $56.6M in revenue for fiscal year 2025.

How fast is Aytu BioPharma, Inc. growing?

Aytu BioPharma, Inc. (AYTU) grew revenue by 1.8% over the past year. Growth has been modest.

Is AYTU profitable?

Aytu BioPharma, Inc. (AYTU) reported a net loss of $34.1M for fiscal year 2025.

Dividend & Returns
What is AYTU's return on equity?

Aytu BioPharma, Inc. (AYTU) has a return on equity (ROE) of -58.1%. Negative ROE indicates the company is unprofitable.

What is Aytu BioPharma, Inc.'s free cash flow?

Aytu BioPharma, Inc. (AYTU) generated $1.6M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in AYTU back in 2007?

Total return calculator · dividends reinvested · 19+ years of data

See returns →