Alnylam Pharmaceuticals, Inc. (ALNY) Price Target Analysis
Updated Jul 2, 2026
Analyst Rating: Buy
Based on 52 analysts44.0% Below Target
ALNY trades 44.0% below Wall Street's consensus target of $450.64.
Current Price$313.04
Average Target$450.64
Target
Current
Low$370.00
Median$447.00
High$530.00
Analyst Target Range
Forward P/E42.1x
(Growth Premium)
PEG Ratio—
Implied Growth+78.1%
(High Growth)
Analyst Spread35.5%
(Moderate)
Price Forecast (1 Year)
Last 12 months price action with 12-month analyst target path
Consensus Scenario Assumptions
The base valuation assumes ALNY achieves its forward estimates and maintains a stable P/E multiple of 42.1x. This scenario reflects the blended consensus of 52 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
ALNY Price Target Analysis
Updated July 7, 2026As of July 7, 2026, Alnylam Pharmaceuticals, Inc. (ALNY) has a Wall Street consensus price target of $450.64, based on estimates from 52 covering analysts. With the stock currently trading at $313.04, this represents a potential upside of +44.0%. The company has a market capitalization of $41.77B.
Analyst price targets range from a low of $370.00 to a high of $530.00, representing a 36% spread in expectations. The median target of $447.00 aligns closely with the consensus average.
The current analyst consensus rating is Buy, with 39 analysts rating the stock as a Buy or Strong Buy,12 rating it Hold, and 1 rating it Sell or Strong Sell. This overwhelmingly bullish sentiment suggests analysts see significant catalysts for upside ahead.
From a valuation perspective, ALNY trades at a trailing P/E of 134.4x and forward P/E of 42.1x. Analysts expect EPS to grow +78.1% over the next year.
Our proprietary valuation model, which blends historical multiples with forward estimates, suggests a base-case price target of $265.60, with bear and bull scenarios of $167.33 and $349.96 respectively. Model confidence stands at 59/100, reflecting moderate uncertainty in projections.
Investment Context: Price targets represent analyst expectations for the next 12 months and should be considered alongside your own research. Targets are based on analysts' assumptions about earnings growth, margins, and market conditions which may change. For sector-specific context, view other Healthcare stocks.
Analyst Sentiment Comparison
Industry Peer AnalysisAvg Peer Upside
+21.1%
Industry Consensus
Avg Forward P/E
13.4x
(Value)
Peers with Coverage
10 / 10
Active Analyst Tracking
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
 IONSIonis Pharmaceuticals, Inc. | $13.7B | $83.18 | $106.50 | +28.0% | Buy | — | 32 |
 ARWRArrowhead Pharmaceuticals, Inc. | $12.2B | $86.55 | $91.00 | +5.1% | Buy | — | 21 |
 NTLAIntellia Therapeutics, Inc. | $2.0B | $17.84 | $26.13 | +46.5% | Buy | — | 39 |
 BEAMBeam Therapeutics Inc. | $3.6B | $35.32 | $48.00 | +35.9% | Buy | — | 27 |
 MRNAModerna, Inc. | $32.4B | $81.80 | $44.88 | -45.1% | Hold | — | 27 |
 CRSPCRISPR Therapeutics AG | $6.0B | $61.89 | $71.67 | +15.8% | Buy | — | 38 |
 REGNRegeneron Pharmaceuticals, Inc. | $67.5B | $649.81 | $836.00 | +28.7% | Buy | 14.0x | 48 |
 BIIBBiogen Inc. | $30.8B | $208.46 | $218.32 | +4.7% | Buy | 14.4x | 48 |
 RAREUltragenyx Pharmaceutical Inc. | $3.3B | $33.70 | $47.11 | +39.8% | Buy | — | 33 |
 BMRNBioMarin Pharmaceutical Inc. | $11.3B | $58.79 | $89.21 | +51.7% | Buy | 11.9x | 41 |
ALNY — Frequently Asked Questions
Quick answers to the most common questions about buying ALNY stock.
What is the ALNY stock price target for 2026?
The consensus Wall Street price target for ALNY is $450.64, representing 44.0% upside from the current price of $313.04. With 52 analysts covering the stock, this strong upside suggests significant value not yet reflected in today's share price.
Is ALNY a buy, sell, or hold?
ALNY has a consensus rating of "Buy" based on 52 Wall Street analysts. The rating breakdown is predominantly bullish, with 39 Buy/Strong Buy ratings. The consensus 12-month price target of $450.64 implies 44.0% upside from current levels.
Is ALNY stock overvalued or undervalued?
At a forward P/E of 42.0985x, ALNY trades at a premium valuation. The consensus price target of $450.64 (44.0% upside) suggests analysts still see growth justifying the multiple.
How high can ALNY stock go?
The most bullish Wall Street analyst has a price target of $530 for ALNY, while the most conservative target is $370. The consensus of $450.64 represents the median expectation. Our quantitative valuation model projects a bull case target of $350 based on optimistic growth and margin assumptions. These targets typically reflect 12-month expectations.
How many analysts cover ALNY stock?
ALNY is heavily covered by Wall Street, with 52 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 39 have Buy ratings, 12 recommend Hold, and 1 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
What is the ALNY stock forecast?
The 12-month ALNY stock forecast based on 52 Wall Street analysts shows a consensus price target of $450.64, with estimates ranging from $370 (bear case) to $530 (bull case). The median consensus rating is "Buy". Our proprietary valuation model produces a base case fair value of $266, with bear/bull scenarios of $167/$350.
What is ALNY's fair value based on fundamentals?
Our quantitative valuation model calculates ALNY's fair value at $266 (base case), with a bear case of $167 and bull case of $350. The model uses discounted cash flow analysis, historical growth rates, and margin mean-reversion to project FY+2 earnings, then applies an appropriate P/E multiple. The model confidence score is 59/100.
What is ALNY's forward P/E ratio?
ALNY trades at a forward P/E ratio of 42.1x based on next-twelve-months earnings estimates compared to a trailing P/E of 134.4x. The lower forward P/E indicates analysts expect earnings growth. A forward P/E is useful for comparing valuations when earnings are expected to change significantly.
Should I buy ALNY stock?
Wall Street analysts are very optimistic on ALNY, with a "Buy" consensus rating and $450.64 price target (44.0% upside). 39 of 52 analysts rate it Buy or Strong Buy. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
Why do ALNY price targets vary so much?
ALNY analyst price targets range from $370 to $530, a 36% moderate spread showing some variance in outlooks. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $450.64 consensus represents the middle ground. Our model's $167-$350 range provides an independent fundamental perspective.
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