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AAPGAscentage Pharma Group International
$19.37$1.8B
Overview & Verdict
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AAPG logoAscentage Pharma Group International(AAPG)Earnings, Financials & Key Ratios

AAPG•NASDAQ
$19.37
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutAscentage Pharma Group International, a clinical-stage biotechnology company, develops therapies for cancers, chronic hepatitis B virus (HBV), and age-related diseases in Mainland China. The company's primary product candidate is HQP1351, a BCR-ABL inhibitor targeting BCR-ABL1 mutants, including those with the T315I mutation. It also develops APG-2575, an oral administered Bcl-2 selective inhibitor for hematologic malignancies and solid tumors; APG-115, an oral small molecule inhibitor of the MDM2-p53 protein-protein interactions to treat solid tumors and hematological malignancies; and APG-1252, a small molecule drug to restore apoptosis through dual inhibition of the Bcl-2 and Bcl-xL proteins for the treatment of small-cell lung cancer, non-small cell lung cancer, neuroendocrine tumor, and non-Hodgkin's lymphoma. In addition, the company is developing APG-1387, a small molecule inhibitor of apoptosis proteins for advanced solid tumors and chronic HBV infection; APG-2449, an oral inhibitor of FAK, ROS1, and ALK kinases; APG-5918, an orally available and selective embryonic ectoderm development inhibitor; APG-265, a MDM2 protein degrader; and UBX1967/1325, which are Bcl-2 inhibitors. In addition, it is also involved in medical research and development; clinical development; clinical trial operation; venture capital investment; rental services; and science and technology promotion services. The company has collaboration relationships with biotechnology and pharmaceutical companies; and research institutions. Ascentage Pharma Group International was founded in 2009 and is headquartered in Suzhou, China.Show more
  • Revenue$558M-43.1%
  • EBITDA-$1.1B-295.9%
  • Net Income-$1.21B-198.2%
  • EPS (Diluted)-13.56-153.0%
  • Gross Margin76.41%-21.3%
  • EBITDA Margin-196.08%-595.3%
  • Operating Margin-211.14%-460.0%
  • Net Margin-216.47%-423.6%
  • ROE-150.25%+36.1%

AAPG Price & Volume

Ascentage Pharma Group International (AAPG) stock price & volume — 10-year historical chart

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Milestone Volatility Masks High R&D Burn Rate

Investment Thesis • Updated 2025Q4

VerdictNeutral
Growth:Mixed
Profitability:Negative
Financial:Healthy
Cash Flow:Burning
Primary Risk:Clinical milestone dependency

Key Thesis Takeaways

  • Ascentage Pharma operates a high-risk, milestone-dependent business model that currently struggles to achieve consistent profitability despite maintaining gross margins above 75%.
  • While the company's $2.5B cash position provides a necessary buffer for its aggressive $587.5M quarterly R&D expenditure, the reliance on non-recurring licensing revenue creates significant earnings instability.
  • Investors should monitor the company's ability to transition from clinical-stage development to sustainable commercial product sales to justify its current $2.0B debt load.

Verdict Logic

while the $2.5B cash reserve offers a current ratio of 1.79, the company's inability to generate consistent positive free cash flow or sustained net income, as seen in the -$640.0M net loss for 2025Q4, warrants a cautious wait-and-see approach.

AAPG Growth Metrics

Ascentage Pharma Group International (AAPG) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years113.98%
3 Years38.61%
TTM258.7%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM9.53%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM82.16%

Return on Capital

10 Years-41.65%
5 Years-43.46%
3 Years-45.55%
Last Year-62.51%

AAPG Recent Earnings

Ascentage Pharma Group International (AAPG) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 1/12 qtrs (50%)●Beat Revenue 1/12 qtrs (100%)
Q2 2026Latest
Mar 24, 2026
Metric
Actual
Est
EPS
$0.65+21.7%
$0.83
Rev
$49M+11.5%
$44M
Q3 2025
Aug 20, 2025
Metric
Actual
Est
EPS
$0.96
—
Rev
$33M
—
Q2 2025
Mar 27, 2025
Metric
Actual
Est
EPS
$1.00-6134.6%
$0.02
Rev
$21M
—
Q4 2024
Dec 31, 2024
Metric
Actual
Est
EPS
$0.25
—
Rev
$21M
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 24, 2026
$0.65vs $0.83+21.7%
$49Mvs $44M+11.5%
Q3 2025Aug 20, 2025
$0.96
$33M
Q2 2025Mar 27, 2025
$1.00vs $0.02-6134.6%
$21M
Q4 2024Dec 31, 2024
$0.25
$21M
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Ascentage Pharma Group International (AAPG)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AAPG logoAAPGAscentage Pharma Group InternationalCurrent
$19.37$1.79B-9.70-43.05%-216.47%-150.25%—
ABBV logoABBVAbbVie Inc.
$254.76$450.11B107.498.57%5.79%67.46%—
BCAB logoBCABBioAtla, Inc.
$4.58$5.78M-0.09-81.82%-2530.85%——
KYMR logoKYMRKymera Therapeutics, Inc.
$114.76$9.37B-31.10-16.72%-612.17%-25.02%—
ARVN logoARVNArvinas, Inc.
$8.45$545.2M-6.60-0.3%-247.54%-44.39%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—

Compare AAPG vs Peers

Ascentage Pharma Group International (AAPG) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ABBV

Most directly comparable listed peer for AAPG.

Scale Benchmark

vs GILD

Larger-name benchmark to compare AAPG against a more recognizable public peer.

Peer Set

Compare Top 5

vs ABBV, BCAB, KYMR, ARVN

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AAPG Frequently Asked Questions

Ascentage Pharma Group International (AAPG) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Ascentage Pharma Group International's revenue?

Ascentage Pharma Group International (AAPG) reported $1.55B in revenue for fiscal year 2025. This represents a 20097% increase from $7.7M in 2016.

How fast is Ascentage Pharma Group International growing?

Ascentage Pharma Group International (AAPG) saw revenue decline by 43.1% over the past year.

Is AAPG profitable?

Ascentage Pharma Group International (AAPG) reported a net loss of $1.64B for fiscal year 2025.

Dividend & Returns
What is AAPG's return on equity?

Ascentage Pharma Group International (AAPG) has a return on equity (ROE) of -150.2%. Negative ROE indicates the company is unprofitable.

What is Ascentage Pharma Group International's free cash flow?

Ascentage Pharma Group International (AAPG) had negative free cash flow of $1.38B in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in AAPG back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →