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VSTMVerastem, Inc.
$4.85$336M
Overview & Verdict
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VSTM logoVerastem, Inc.(VSTM)Earnings, Financials & Key Ratios

VSTM•NASDAQ
$4.85
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutVerastem, Inc., a development-stage biopharmaceutical company, focusing on developing and commercializing drugs for the treatment of cancer. Its product in development includes VS-6766, a dual rapidly accelerated fibrosarcoma (RAF)/mitogen-activated protein kinase (MEK) clamp that blocks MEK kinase activity and the ability of RAF to phosphorylate MEK. The company also engages in developing RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of VS-6766 and in combination with defactinib, an oral small molecule inhibitor of focal adhesion kinase (FAK) in patients with recurrent low grade serous ovarian cancer; and RAMP 202, which is in Phase 2 trial to evaluate the safety of VS-6766 in combination with defactinib in patients with KRAS and BRAF mutant non-small cell lung cancer following treatment with a platinum-based regimen and immune checkpoint inhibitor. Verastem, Inc. has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing VS-6766; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer's inhibitors of FAK for therapeutic, diagnostic and prophylactic uses in humans. In addition, it has clinical collaboration agreement with Amgen, Inc. to evaluate the combination of VS-6766 with Amgen's KRAS-G12C inhibitor LUMAKRASTM which in Phase 1/2 trial entitled RAMP 203. The company was incorporated in 2010 and is headquartered in Needham, Massachusetts.Show more
  • Revenue$31M+209.1%
  • EBITDA-$169M-47.4%
  • Net Income-$209M-60.3%
  • EPS (Diluted)-3.02+17.5%
  • Gross Margin82.86%-17.1%
  • EBITDA Margin-547.98%+52.3%
  • Operating Margin-550.33%+52.1%
  • Net Margin-677.59%+48.1%
  • ROE-1480.15%-61.3%

VSTM Price & Volume

Verastem, Inc. (VSTM) stock price & volume — 10-year historical chart

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Clinical R&D Intensity Drives Persistent Capital Deficits

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary clinical trial outcomes

Key Thesis Takeaways

  • Verastem remains a high-risk, binary-outcome biotechnology play characterized by extreme revenue volatility tied to non-recurring milestone payments rather than sustainable commercial operations.
  • The company's reliance on aggressive R&D spending, which reached $38.2 million in 2026Q1, necessitates ongoing capital raises that threaten to further dilute existing shareholders.
  • Investors should monitor the clinical progression of the RAF/MEK platform, as the current burn rate and rising debt levels suggest a precarious path toward long-term financial viability.

Verdict Logic

the company's unsustainable cash burn, evidenced by a $52.1 million free cash flow deficit in 2026Q1, poses a significant risk of further shareholder dilution and balance sheet instability.

VSTM Growth Metrics

Verastem, Inc. (VSTM) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-18.97%
3 Years128.36%
TTM395.85%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-30.28%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM23.53%

Return on Capital

10 Years-80.42%
5 Years-98.9%
3 Years-117.07%
Last Year-139.03%

VSTM Recent Earnings

Verastem, Inc. (VSTM) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 3/12 qtrs (43%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.46+0.0%
$0.46
Rev
$19M-12.9%
$21M
Q2 2026
Mar 4, 2026
Metric
Actual
Est
EPS
$0.39+20.4%
$0.49
Rev
$18M+3.7%
$17M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$1.35-164.7%
$0.51
Rev
$11M-32.0%
$17M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.39+54.1%
$0.85
Rev
$2M-62.5%
$6M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.46vs $0.46+0.0%
$19Mvs $21M-12.9%
Q2 2026Mar 4, 2026
$0.39vs $0.49+20.4%
$18Mvs $17M+3.7%
Q4 2025Nov 4, 2025
$1.35vs $0.51-164.7%
$11Mvs $17M-32.0%
Q3 2025Aug 7, 2025
$0.39vs $0.85+54.1%
$2Mvs $6M-62.5%
Based on last 12 quarters of dataView full earnings history →

Latest VSTM News

Recent stock market news and headlines for Verastem, Inc. (VSTM)

Business Wire·5 days ago
Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced the grant of 399,750 restricted stock units to 30 new employees and the grant of stock options to purchase 91,000 shares of its common stock to one new employee. The awards were granted pursuant to the Nasdaq inducement grant exception as an inducement material to the employee's acceptance of employment wit.

Seeking Alpha·Jun 23, 2026
Verastem, Inc. (VSTM) Discusses Preliminary TARGET-D 101 Data for VS-7375 in KRAS G12D Mutated Cancers Transcript

Verastem, Inc. (VSTM) Discusses Preliminary TARGET-D 101 Data for VS-7375 in KRAS G12D Mutated Cancers Transcript

Business Wire·Jun 23, 2026
VS-7375 Demonstrates Clinical Activity with a Favorable Safety and Tolerability Profile in TARGET-D 101 Phase 1/2 Clinical Trial in Patients with Advanced KRAS G12D-Mutated Solid Tumors

BOSTON--(BUSINESS WIRE)---- $VSTM #CRC--VS-7375 (investigational KRAS G12D ON/OFF inhibitor) demonstrates clinical activity with a favorable safety profile in TARGET-D 101 clinical trial.

Seeking Alpha·Jun 17, 2026
Verastem: 'Buy' Positive RAMP-205 Data And Extensive VS-7375 Registration Program

Verastem, Inc. is maintained at a Buy rating, driven by upcoming clinical catalysts and positive early-stage data in KRAS G12D mutant solid tumors. VSTM expects key data readouts from the TARGET-D 101 phase 1/2 study in 2026 and is advancing three phase 2 registration-directed studies for PDAC, NSCLC, and CRC for VS-7375. Positive phase 1b/2a RAMP 205 results in 1st-line metastatic PDAC (86% OS at 6 months, 52% cORR) support further development of avutometinib/defactinib combinations.

Benzinga·Jun 17, 2026
Verastem Stock Jumps As Data Shows Strong Survival Trends In Pancreatic Cancer

Verastem, Inc. (NASDAQ:VSTM) stock is trading higher on Wednesday as the company announced positive updated results from its RAMP 205 trial, which evaluates the efficacy of its drug combination in treating metastatic pancreatic cancer.

Peers Comparison

Key metrics vs top competitors for Verastem, Inc. (VSTM)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
VSTM logoVSTMVerastem, Inc.Current
$4.85$336.17M-1.61209.14%-677.59%-1480.15%—
KPTI logoKPTIKaryopharm Therapeutics Inc.
$10.05$85.8M-0.560.57%-129.02%——
MGNX logoMGNXMacroGenics, Inc.
$4.75$301.92M-4.030.78%-44.79%-147.8%—
TGTX logoTGTXTG Therapeutics, Inc.
$53.52$8.19B19.3287.32%65.95%87.36%—
IMVT logoIMVTImmunovant, Inc.
$40.09$8.23B-14.47——-68.16%—
PRME logoPRMEPrime Medicine, Inc.
$3.99$720.66M-2.9655.28%-4917.55%-188.82%—

Compare VSTM vs Peers

Verastem, Inc. (VSTM) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KPTI

Most directly comparable listed peer for VSTM.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare VSTM against a more recognizable public peer.

Peer Set

Compare Top 5

vs KPTI, MGNX, TGTX, IMVT

VSTM SEC Filings & Documents

Verastem, Inc. (VSTM) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Mar 4, 2026·SEC

Material company update

Feb 4, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 4, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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VSTM Frequently Asked Questions

Verastem, Inc. (VSTM) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Verastem, Inc.'s revenue?

Verastem, Inc. (VSTM) reported $49.6M in revenue for fiscal year 2025.

How fast is Verastem, Inc. growing?

Verastem, Inc. (VSTM) grew revenue by 209.1% over the past year. This is strong growth.

Is VSTM profitable?

Verastem, Inc. (VSTM) reported a net loss of $194.0M for fiscal year 2025.

Dividend & Returns
What is VSTM's return on equity?

Verastem, Inc. (VSTM) has a return on equity (ROE) of -1480.2%. Negative ROE indicates the company is unprofitable.

What is Verastem, Inc.'s free cash flow?

Verastem, Inc. (VSTM) had negative free cash flow of $150.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in VSTM back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →