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TRVITrevi Therapeutics, Inc.
$19.50$2.8B
Overview & Verdict
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TRVI logoTrevi Therapeutics, Inc.(TRVI)Earnings, Financials & Key Ratios

TRVI•NASDAQ
$19.50
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutTrevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of Haduvio to treat serious neurologically mediated conditions. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase IIb/III clinical trial for the treatment of chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut.Show more
  • Revenue$0
  • EBITDA-$49M+4.3%
  • Net Income-$43M+10.8%
  • EPS (Diluted)-0.29+38.3%
  • ROE-30.23%+42.5%

TRVI Price & Volume

Trevi Therapeutics, Inc. (TRVI) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Trevi Liquidity Position

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and dilution

Key Thesis Takeaways

  • Trevi Therapeutics remains a high-risk, clinical-stage entity characterized by a complete lack of commercial revenue and persistent quarterly operating losses that reached $14.9 million in 2026Q1.
  • The company's reliance on R&D-heavy spending, which consistently consumes millions in quarterly capital, necessitates frequent external financing that threatens to dilute existing shareholders.
  • Investors should monitor the firm's ability to reach critical clinical milestones before its $19.4 million cash balance is fully exhausted by ongoing operational burn.

Verdict Logic

the company's inability to generate revenue combined with a rapid cash burn rate that reduced reserves to $19.4 million in 2026Q1 suggests imminent dilution risk for investors.

TRVI Growth Metrics

Trevi Therapeutics, Inc. (TRVI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM3.67%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM28.06%

Return on Capital

10 Years-116.35%
5 Years-53.3%
3 Years-41.95%
Last Year-34.73%

TRVI Recent Earnings

Trevi Therapeutics, Inc. (TRVI) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$0.09-28.6%
$0.07
Rev
—
—
Q2 2026
Mar 17, 2026
Metric
Actual
Est
EPS
$0.06+40.0%
$0.10
Rev
—
—
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.08+20.0%
$0.10
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.09+10.0%
$0.10
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.09vs $0.07-28.6%
—
Q2 2026Mar 17, 2026
$0.06vs $0.10+40.0%
—
Q4 2025Nov 13, 2025
$0.08vs $0.10+20.0%
—
Q3 2025Aug 7, 2025
$0.09vs $0.10+10.0%
—
Based on last 12 quarters of dataView full earnings history →

Latest TRVI News

Recent stock market news and headlines for Trevi Therapeutics, Inc. (TRVI)

GlobeNewsWire·Jun 17, 2026
Trevi Therapeutics Announces Upcoming June and July Event Schedule

NEW HAVEN, Conn., June 17, 2026 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc.  (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC), today announced that senior management will attend several upcoming events in June and July.

Peers Comparison

Key metrics vs top competitors for Trevi Therapeutics, Inc. (TRVI)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TRVI logoTRVITrevi Therapeutics, Inc.Current
$19.50$2.77B-67.24——-30.23%—
IDYA logoIDYAIDEAYA Biosciences, Inc.
$40.51$3.56B-31.653024.43%-62.17%-13.96%—
PTCT logoPTCTPTC Therapeutics, Inc.
$89.20$7.4B11.47114.51%-22.58%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$26.20$4.49B11.4411.87%34.3%35.65%—
INVA logoINVAInnoviva, Inc.
$22.25$1.64B6.7418.52%118.91%47.59%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$323.95$9.36B-24.03-100%—-43.02%—

Compare TRVI vs Peers

Trevi Therapeutics, Inc. (TRVI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IDYA

Most directly comparable listed peer for TRVI.

Scale Benchmark

vs IQV

Larger-name benchmark to compare TRVI against a more recognizable public peer.

Peer Set

Compare Top 5

vs IDYA, PTCT, ACAD, INVA

TRVI SEC Filings & Documents

Trevi Therapeutics, Inc. (TRVI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

Apr 17, 2026·SEC

Material company update

Mar 17, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 18, 2025·SEC

FY 2024

Mar 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 5, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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TRVI Frequently Asked Questions

Trevi Therapeutics, Inc. (TRVI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is TRVI profitable?

Trevi Therapeutics, Inc. (TRVI) reported a net loss of $45.6M for fiscal year 2025.

Dividend & Returns
What is TRVI's return on equity?

Trevi Therapeutics, Inc. (TRVI) has a return on equity (ROE) of -30.2%. Negative ROE indicates the company is unprofitable.

What is Trevi Therapeutics, Inc.'s free cash flow?

Trevi Therapeutics, Inc. (TRVI) had negative free cash flow of $31.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TRVI back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →