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TNGXTango Therapeutics, Inc.
$30.12$3.5B
Overview & Verdict
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TNGX logoTango Therapeutics, Inc.(TNGX)Earnings, Financials & Key Ratios

TNGX•NASDAQ
$29.94
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutTango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company also develops Ubiquitin-specific protease 1, an inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. Tango Therapeutics, Inc. has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. The company was founded in 2017 and is based in Cambridge, Massachusetts.Show more
  • Revenue$62M+48.3%
  • EBITDA-$109M+23.8%
  • Net Income-$102M+22.0%
  • EPS (Diluted)-0.87+26.9%
  • Gross Margin96.34%-3.7%
  • EBITDA Margin-174.74%+48.6%
  • Operating Margin-178.39%+48.5%
  • Net Margin-162.85%+47.4%
  • ROE-37.23%+35.3%

TNGX Price & Volume

Tango Therapeutics, Inc. (TNGX) stock price & volume — 10-year historical chart

Loading chart...

Collaboration Milestone Volatility Masks Structural Cash Burn

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Adequate
Cash Flow:Burning
Primary Risk:Collaboration revenue concentration risk

Key Thesis Takeaways

  • Tango Therapeutics remains a high-risk, clinical-stage entity whose financial viability is tethered to the unpredictable timing of milestone payments from its sole collaboration partner.
  • While the company maintains a $157.8 million cash position as of 2026Q1, the persistent quarterly R&D spend exceeding $30 million creates a structural dependency on external funding.
  • Investors should monitor the company's ability to advance its synthetic lethality pipeline without further dilutive financing, given the absence of sustainable commercial revenue.

Verdict Logic

the company's reliance on a single counterparty for revenue and its persistent negative free cash flow, which resulted in a $44.4 million outflow in 2026Q1, present significant risks to long-term shareholder value.

TNGX Growth Metrics

Tango Therapeutics, Inc. (TNGX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years52.13%
3 Years35.89%
TTM39.04%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM18.93%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM31.41%

Return on Capital

10 Years-37.1%
5 Years-31.16%
3 Years-36.93%
Last Year-33.96%

TNGX Recent Earnings

Tango Therapeutics, Inc. (TNGX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 5/12 qtrs (50%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.32-2.0%
$0.31
Rev
—
$578,091
Q2 2026
Mar 5, 2026
Metric
Actual
Est
EPS
$0.29+6.5%
$0.31
Rev
—
$500,400
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$0.13+1200.0%
$0.01
Rev
$54M+9578.2%
$556,000
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$0.35+0.0%
$0.35
Rev
$3M-50.3%
$6M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.32vs $0.31-2.0%
—vs $578,091
Q2 2026Mar 5, 2026
$0.29vs $0.31+6.5%
—vs $500,400
Q4 2025Nov 4, 2025
$0.13vs $0.01+1200.0%
$54Mvs $556,000+9578.2%
Q3 2025Aug 5, 2025
$0.35vs $0.35+0.0%
$3Mvs $6M-50.3%
Based on last 12 quarters of dataView full earnings history →

Latest TNGX News

Recent stock market news and headlines for Tango Therapeutics, Inc. (TNGX)

Zacks Investment Research·5 days ago
Is TNGX Stock Still Worth Buying After Its Huge Rally in 2026?

Tango Therapeutics' strong 2026 rally reflects promising clinical progress, but its premium valuation puts upcoming study results at the center of the next move.

Zacks Investment Research·5 days ago
Tango Therapeutics Rides a New Precision Oncology Trend in 2026

TNGX is advancing precision oncology with MTAP-targeted therapies and 2026 data readouts that could test its clinical and commercial potential.

Zacks Investment Research·5 days ago
TNGX Stock Outlook Hinges on Vopimetostat and Key 2026 Catalysts

Tango Therapeutics enters a pivotal phase as vopimetostat drives its investment case, with 2026 clinical updates set to test its focused oncology pipeline.

GlobeNewsWire·Jun 22, 2026
Tango Therapeutics Appoints Robert Azelby to Board of Directors

BOSTON, June 22, 2026 (GLOBE NEWSWIRE) -- Tango Therapeutics, Inc. (NASDAQ: TNGX), a clinical-stage biotechnology company committed to discovering and delivering the next generation of precision cancer medicines, today announced the appointment of Robert Azelby to its Board of Directors. Mr. Azelby brings more than three decades of leadership experience across the biopharmaceutical industry, including deep expertise in oncology commercialization, corporate strategy, company building and board governance. His appointment comes as Tango advances vopimetostat, its investigational PRMT5 inhibitor with first- and best-in-class potential, toward potential late-stage development for patients with pancreatic cancer.

Peers Comparison

Key metrics vs top competitors for Tango Therapeutics, Inc. (TNGX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TNGX logoTNGXTango Therapeutics, Inc.Current
$29.94$3.48B-34.4148.29%-162.85%-37.23%—
RVMD logoRVMDRevolution Medicines, Inc.
$189.99$40.39B-31.93——-83.22%—
KYMR logoKYMRKymera Therapeutics, Inc.
$114.76$9.37B-31.10-16.72%-612.17%-25.02%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$313.50$9.06B-23.26-100%—-43.02%—
AUPH logoAUPHAurinia Pharmaceuticals Inc.
$15.49$1.99B7.4820.38%99.97%64.48%—
PMVP logoPMVPPMV Pharmaceuticals, Inc.
$1.21$64.26M-0.81——-68.98%—

Compare TNGX vs Peers

Tango Therapeutics, Inc. (TNGX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RVMD

Most directly comparable listed peer for TNGX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare TNGX against a more recognizable public peer.

Peer Set

Compare Top 5

vs RVMD, KYMR, PRAX, AUPH

TNGX SEC Filings & Documents

Tango Therapeutics, Inc. (TNGX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

May 8, 2026·SEC

Material company update

Apr 15, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 5, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Mar 18, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 5, 2025·SEC

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TNGX Frequently Asked Questions

Tango Therapeutics, Inc. (TNGX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Tango Therapeutics, Inc.'s revenue?

Tango Therapeutics, Inc. (TNGX) reported $57.0M in revenue for fiscal year 2025. This represents a 131% increase from $24.6M in 2019.

How fast is Tango Therapeutics, Inc. growing?

Tango Therapeutics, Inc. (TNGX) grew revenue by 48.3% over the past year. This is strong growth.

Is TNGX profitable?

Tango Therapeutics, Inc. (TNGX) reported a net loss of $107.2M for fiscal year 2025.

Dividend & Returns
What is TNGX's return on equity?

Tango Therapeutics, Inc. (TNGX) has a return on equity (ROE) of -37.2%. Negative ROE indicates the company is unprofitable.

What is Tango Therapeutics, Inc.'s free cash flow?

Tango Therapeutics, Inc. (TNGX) had negative free cash flow of $142.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TNGX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →