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SLPSimulations Plus, Inc.
$18.28$369M
Overview & Verdict
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SLP logoSimulations Plus, Inc.(SLP)Earnings, Financials & Key Ratios

SLP•NASDAQ
$18.28
Price updated Jul 7, 2026
SectorHealthcareIndustryHealthcare ITSub-IndustryLife Sciences and Precision Medicine Software
AboutSimulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through four segments: Simulations Plus, Cognigen, DILIsym, and Lixoft. The company offers GastroPlus, which simulates the absorption and drug interaction of compounds administered to humans and animals; and DDDPlus and MembranePlus simulation products. It also provides products based on mechanistic and mathematical models, such as DILIsym, a quantitative systems pharmacology software; NAFLDsym; IPFsym; RENAsym; and MITOsym. In addition, the company provides Absorption, Distribution, Metabolism, Excretion, and Toxicity Predictor for chemistry-based computer program that takes molecular structures as inputs and predicts their properties; and MedChem Designer, as well as modeling and simulation products comprising MonolixSuite and PKPlus. Further, it provides population modeling and simulation contract research services; training and consulting services designed to accelerate pharmacometrics studies; and clinical-pharmacology-based consulting services in support of regulatory submissions. The company serves pharmaceutical, biotechnology, agrochemical, cosmetics, and food companies, as well as academic and regulatory agencies. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Lancaster, California.Show more
  • Revenue$79M+13.1%
  • EBITDA-$63M-630.0%
  • Net Income-$65M-750.2%
  • EPS (Diluted)-3.22-757.1%
  • Gross Margin58.38%-5.3%
  • EBITDA Margin-78.96%-568.6%
  • Operating Margin-89.33%-1120.1%
  • Net Margin-81.74%-674.9%
  • ROE-42.13%-845.9%

SLP Price & Volume

Simulations Plus, Inc. (SLP) stock price & volume — 10-year historical chart

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Revenue Growth Masks Persistent Bottom Line Volatility

Investment Thesis • Updated 2026Q2

VerdictNeutral
Growth:Expanding
Profitability:Strained
Financial:Healthy
Cash Flow:Mixed
Primary Risk:Regulatory dependency and margin volatility

Key Thesis Takeaways

  • Simulations Plus demonstrates resilient top-line expansion with 13.09% year-over-year growth, yet the firm faces significant challenges in stabilizing profitability due to erratic operating margins that swung from 24.3% to negative territory.
  • While the company maintains a healthy liquidity buffer with $25.7M in cash, the erosion of retained earnings into a $29.2M deficit warrants caution regarding long-term capital structure stability.
  • Investors should monitor the firm's ability to convert its proprietary modeling software demand into consistent earnings, as current valuation metrics like the negative TTM P/E of -5.65 reflect significant bottom-line noise.

Verdict Logic

while the company maintains a solid current ratio of 5.47, the persistent erosion of equity and the volatility in net income suggest that investors should wait for more consistent profitability before committing capital at the current 20.98 forward P/E.

SLP Growth Metrics

Simulations Plus, Inc. (SLP) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years15.77%
5 Years13.74%
3 Years13.67%
TTM2.51%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-964.83%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-988.81%

Return on Capital

10 Years9.99%
5 Years-4.17%
3 Years-12.01%
Last Year-44.1%

SLP Recent Earnings

Simulations Plus, Inc. (SLP) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
Apr 9, 2026
Metric
Actual
Est
EPS
$0.35+29.6%
$0.27
Rev
$24M+12.2%
$22M
Q1 2026
Jan 8, 2026
Metric
Actual
Est
EPS
$0.13-27.8%
$0.18
Rev
$18M+2.0%
$18M
Q4 2025
Dec 1, 2025
Metric
Actual
Est
EPS
$0.10+0.0%
$0.10
Rev
$17M+0.4%
$17M
Q3 2025
Jul 14, 2025
Metric
Actual
Est
EPS
$0.45+73.1%
$0.26
Rev
$20M-2.7%
$21M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 9, 2026
$0.35vs $0.27+29.6%
$24Mvs $22M+12.2%
Q1 2026Jan 8, 2026
$0.13vs $0.18-27.8%
$18Mvs $18M+2.0%
Q4 2025Dec 1, 2025
$0.10vs $0.10+0.0%
$17Mvs $17M+0.4%
Q3 2025Jul 14, 2025
$0.45vs $0.26+73.1%
$20Mvs $21M-2.7%
Based on last 12 quarters of dataView full earnings history →

Latest SLP News

Recent stock market news and headlines for Simulations Plus, Inc. (SLP)

PRNewsWire·1 day ago
Johnson Fistel Investigates Simulations Plus Following Revenue Guidance Cut and Accounting Disclosures

SAN DIEGO, July 6, 2026 /PRNewswire/ -- Johnson Fistel, PLLP is investigating Simulations Plus, Inc. (NASDAQ: SLP) on behalf of investors who suffered losses and whether those losses may be recoverable under federal securities laws. On April 3, 2025, Simulations Plus reported second-quarter fiscal 2025 financial results and maintained full-year revenue guidance of $90 million to $93 million.

Business Wire·Jun 23, 2026
Simulations Plus Advances Agentic Drug Development with NVIDIA BioNeMo Agent Toolkit

RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Simulations Plus, Inc. (Nasdaq: SLP) (“Simulations Plus” or the “Company”), a global leader in model-informed and AI-accelerated drug development that helps advance biopharma innovation, today announced it is building the agentic layer of Composer, its AI-native platform for model-informed drug development, using the NVIDIA BioNeMo Agent Toolkit. The initiative expands the companies' collaboration announced in May 2026, extending their work in GPU-.

Peers Comparison

Key metrics vs top competitors for Simulations Plus, Inc. (SLP)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SLP logoSLPSimulations Plus, Inc.Current
$18.28$369.36M-5.6813.09%-81.74%-42.13%—
VEEV logoVEEVVeeva Systems Inc.
$192.30$31.24B35.3516.34%28.37%13.36%—
CERT logoCERTCertara, Inc.
$7.17$1.12B-717.008.75%-3.6%-1.43%—
SCYX logoSCYXSCYNEXIS, Inc.
$4.61$28.99M-3.39449.95%-120.51%-57.16%—
DSGN logoDSGNDesign Therapeutics, Inc.
$14.71$918.74M-12.06——-33.07%—
SDGR logoSDGRSchrödinger, Inc.
$16.49$1.23B-11.7023.29%-40.6%-30.85%—

Compare SLP vs Peers

Simulations Plus, Inc. (SLP) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs VEEV

Most directly comparable listed peer for SLP.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SLP against a more recognizable public peer.

Peer Set

Compare Top 5

vs VEEV, CERT, SCYX, DSGN

SLP SEC Filings & Documents

Simulations Plus, Inc. (SLP) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jun 17, 2026·SEC

Material company update

Jun 16, 2026·SEC

Material company update

Apr 9, 2026·SEC

10-K Annual Reports

3
FY 2025

Dec 1, 2025·SEC

FY 2024

Oct 30, 2024·SEC

FY 2023

Oct 27, 2023·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 10, 2026·SEC

FY 2026

Jan 9, 2026·SEC

FY 2025

Jul 15, 2025·SEC

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SLP Frequently Asked Questions

Simulations Plus, Inc. (SLP) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Simulations Plus, Inc.'s revenue?

Simulations Plus, Inc. (SLP) reported $80.5M in revenue for fiscal year 2025. This represents a 2998% increase from $2.6M in 1996.

How fast is Simulations Plus, Inc. growing?

Simulations Plus, Inc. (SLP) grew revenue by 13.1% over the past year. This is steady growth.

Is SLP profitable?

Simulations Plus, Inc. (SLP) reported a net loss of $62.8M for fiscal year 2025.

Dividend & Returns
What is SLP's return on equity?

Simulations Plus, Inc. (SLP) has a return on equity (ROE) of -42.1%. Negative ROE indicates the company is unprofitable.

What is Simulations Plus, Inc.'s free cash flow?

Simulations Plus, Inc. (SLP) generated $22.9M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in SLP back in 1996?

Total return calculator · dividends reinvested · 30+ years of data

See returns →