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KZRKezar Life Sciences, Inc.
$7.29$54M
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KZR logoKezar Life Sciences, Inc.(KZR)Earnings, Financials & Key Ratios

KZR•NASDAQ
$7.29
Price updated Jun 20, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutKezar Life Sciences, Inc., a clinical-stage biotechnology company, engages in the discovery and development of novel small molecule therapeutics to treat unmet needs in immune-mediated diseases and cancer in the United States. The company's lead product candidate is KZR-616, a selective immunoproteasome inhibitor that is in Phase 2 clinical trials for various indications, including lupus nephritis, dermatomyositis, and polymyositis; and Phase 1b clinical trials in systemic lupus erythematosus and lupus nephritis. Its preclinical products include KZR-261, a novel first-in-class protein secretion inhibitor for the treatment of KZR-261; and KZR-TBD for the treatment of oncology and immunology. The company was incorporated in 2015 and is based in South San Francisco, California.Show more
  • Revenue$0
  • EBITDA-$51M+42.6%
  • Net Income-$56M+33.1%
  • EPS (Diluted)-7.66-566.1%
  • ROE-59.93%-9.0%

KZR Price & Volume

Kezar Life Sciences, Inc. (KZR) stock price & volume — 10-year historical chart

Loading chart...

Clinical Attrition Drives Severe Operational Contraction

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial failure risk

Key Thesis Takeaways

  • Kezar Life Sciences faces a precarious outlook as the company has effectively pivoted away from its primary clinical programs following significant safety setbacks.
  • The drastic reduction in R&D spending from $22.6M in 2023Q4 to $1.5M in 2026Q1 suggests a lack of viable near-term growth drivers.
  • Investors should monitor the company's ability to preserve its remaining $66.2M cash balance while navigating the absence of any revenue-generating commercial pipeline.

Verdict Logic

the company's lack of revenue and the rapid depletion of total assets from $221.2M in 2023Q4 to $68.0M in 2026Q1 suggest a distressed asset profile with limited upside.

KZR Growth Metrics

Kezar Life Sciences, Inc. (KZR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM42.48%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-9.79%

Return on Capital

10 Years-43.14%
5 Years-42.74%
3 Years-51.44%
Last Year-53.77%

KZR Recent Earnings

Kezar Life Sciences, Inc. (KZR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 1/12 qtrs (100%)
Q2 2026Latest
May 11, 2026
Metric
Actual
Est
EPS
$0.78+20.4%
$0.98
Rev
—
$1M
Q2 2026
Mar 27, 2026
Metric
Actual
Est
EPS
$1.99-52.0%
$1.31
Rev
—
$333,330
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$1.53+15.5%
$1.81
Rev
—
—
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$1.87+13.0%
$2.15
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$0.78vs $0.98+20.4%
—vs $1M
Q2 2026Mar 27, 2026
$1.99vs $1.31-52.0%
—vs $333,330
Q4 2025Nov 12, 2025
$1.53vs $1.81+15.5%
—
Q3 2025Aug 13, 2025
$1.87vs $2.15+13.0%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Kezar Life Sciences, Inc. (KZR)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
KZR logoKZRKezar Life Sciences, Inc.Current
$7.29$53.86M-0.95——-59.93%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$26.07$3.26B-200.5491.34%-0.57%-1.41%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$313.50$9.06B-23.26-100%—-43.02%—
TGTX logoTGTXTG Therapeutics, Inc.
$53.52$8.19B19.3287.32%65.95%87.36%—
CABA logoCABACabaletta Bio, Inc.
$3.01$490.79M-1.84——-131.58%—

Compare KZR vs Peers

Kezar Life Sciences, Inc. (KZR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for KZR.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare KZR against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARQT, PRAX, TGTX

KZR SEC Filings & Documents

Kezar Life Sciences, Inc. (KZR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 11, 2026·SEC

Material company update

Apr 3, 2026·SEC

Material company update

Mar 30, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 27, 2026·SEC

FY 2025

Mar 25, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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KZR Frequently Asked Questions

Kezar Life Sciences, Inc. (KZR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is KZR profitable?

Kezar Life Sciences, Inc. (KZR) reported a net loss of $45.2M for fiscal year 2025.

Dividend & Returns
What is KZR's return on equity?

Kezar Life Sciences, Inc. (KZR) has a return on equity (ROE) of -59.9%. Negative ROE indicates the company is unprofitable.

What is Kezar Life Sciences, Inc.'s free cash flow?

Kezar Life Sciences, Inc. (KZR) had negative free cash flow of $42.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in KZR back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →