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DSGNDesign Therapeutics, Inc.
$14.85$927M
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DSGN logoDesign Therapeutics, Inc.(DSGN)Earnings, Financials & Key Ratios

DSGN•NASDAQ
$14.85
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryRNA and Genome Editing Developers
AboutDesign Therapeutics, Inc. a preclinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of genetic diseases caused by nucleotide repeat expansions. The company's portfolio of products comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function, eventually leading to neurological, cardiac, and metabolic dysfunction; and Myotonic Dystrophy Type-1 (DM1), a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs. It is also developing GeneTAC product candidate portfolio for the treatment of other nucleotide repeat expansion-driven monogenic diseases, such as Fragile X syndrome, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia, Huntington disease, and spinobulbar muscular atrophy. Design Therapeutics, Inc. was incorporated in 2017 and is headquartered in Carlsbad, California.Show more
  • Revenue$0
  • EBITDA-$79M-27.6%
  • Net Income-$70M-40.7%
  • EPS (Diluted)-1.22-38.6%
  • ROE-30.7%-60.9%

DSGN Price & Volume

Design Therapeutics, Inc. (DSGN) stock price & volume — 10-year historical chart

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Persistent Clinical Burn Threatens Future Liquidity Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Critical liquidity and runway

Key Thesis Takeaways

  • Design Therapeutics faces a precarious financial outlook as it continues to fund its GeneTAC platform development without any revenue generation, leading to a cumulative retained earnings deficit of $314.6 million.
  • The company's reliance on external financing is increasingly urgent given the rapid depletion of cash reserves, which fell from $45.7 million in 2024Q2 to $12.8 million by 2026Q1.
  • Investors should monitor the company's ability to secure additional capital, as the current quarterly operating loss of $19.7 million significantly outpaces the remaining liquidity buffer.

Verdict Logic

the company's cash position has plummeted to $12.8 million as of 2026Q1, creating a critical liquidity risk that necessitates immediate and likely dilutive financing to sustain operations.

DSGN Growth Metrics

Design Therapeutics, Inc. (DSGN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-24.05%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-21.21%

Return on Capital

10 Years-29.37%
5 Years-24.04%
3 Years-28.08%
Last Year-34.79%

DSGN Recent Earnings

Design Therapeutics, Inc. (DSGN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 10/12 qtrs (83%)
Q2 2026Latest
Apr 28, 2026
Metric
Actual
Est
EPS
$0.29+19.4%
$0.36
Rev
—
—
Q2 2026
Mar 9, 2026
Metric
Actual
Est
EPS
$0.27+28.9%
$0.38
Rev
—
—
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.30+11.8%
$0.34
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.34-6.3%
$0.32
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 28, 2026
$0.29vs $0.36+19.4%
—
Q2 2026Mar 9, 2026
$0.27vs $0.38+28.9%
—
Q4 2025Nov 5, 2025
$0.30vs $0.34+11.8%
—
Q3 2025Aug 7, 2025
$0.34vs $0.32-6.3%
—
Based on last 12 quarters of dataView full earnings history →

Latest DSGN News

Recent stock market news and headlines for Design Therapeutics, Inc. (DSGN)

Seeking Alpha·Jun 24, 2026
Design Therapeutics: FA Early Data And FDA Discussions Are Promising Catalysts

Design Therapeutics has its proprietary GeneTAC platform. This gives them a small-molecule way to target repeat-expansion diseases. Their main value driver and drug candidate is DT-216P2 for FA. DSGN's trial on DT-216P2 is RESTORE-FA. This trial produced data that I believe makes DT-216P2 much more credible.

Peers Comparison

Key metrics vs top competitors for Design Therapeutics, Inc. (DSGN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DSGN logoDSGNDesign Therapeutics, Inc.Current
$14.85$927.49M-12.17——-30.7%—
FULC logoFULCFulcrum Therapeutics, Inc.
$3.72$201.29M-3.15-100%—-27.8%—
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$26.07$3.26B-200.5491.34%-0.57%-1.41%—
BEAM logoBEAMBeam Therapeutics Inc.
$35.32$3.63B-43.60120.01%-49.17%-5.89%—

Compare DSGN vs Peers

Design Therapeutics, Inc. (DSGN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs FULC

Most directly comparable listed peer for DSGN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare DSGN against a more recognizable public peer.

Peer Set

Compare Top 5

vs FULC, EXAS, IMVT, ARQT

DSGN SEC Filings & Documents

Design Therapeutics, Inc. (DSGN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Apr 1, 2026·SEC

Material company update

Mar 9, 2026·SEC

10-K Annual Reports

5
FY 2026

Mar 9, 2026·SEC

FY 2025

Mar 10, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 28, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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DSGN Frequently Asked Questions

Design Therapeutics, Inc. (DSGN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DSGN profitable?

Design Therapeutics, Inc. (DSGN) reported a net loss of $69.7M for fiscal year 2025.

Dividend & Returns
What is DSGN's return on equity?

Design Therapeutics, Inc. (DSGN) has a return on equity (ROE) of -30.7%. Negative ROE indicates the company is unprofitable.

What is Design Therapeutics, Inc.'s free cash flow?

Design Therapeutics, Inc. (DSGN) had negative free cash flow of $54.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in DSGN back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →