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CRLCharles River Laboratories International, Inc.
$228.68$11.0B
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CRL logoCharles River Laboratories International, Inc.(CRL)Earnings, Financials & Key Ratios

CRL•NYSE
$228.68
Price updated Jul 7, 2026
SectorHealthcareIndustryDiagnostics & ResearchSub-IndustryContract Research and Preclinical Services
AboutCharles River Laboratories International, Inc., a non-clinical contract research organization, provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. It operates through three segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions (Manufacturing). The RMS segment produces and sells rodent research model strains and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening non-clinical drug candidates, including research models, genetically engineered models and services, insourcing solutions, and research animal diagnostic services. The DSA segment offers early and in vivo discovery services for the identification and validation of novel targets, chemical compounds, and antibodies through delivery of non-clinical drug and therapeutic candidates ready for safety assessment; and safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services. The Manufacturing segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products. This segment also offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and avian vaccine services that provide specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products used to manufacture vaccines. The company also provides contract vivarium operation services to biopharmaceutical clients. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.Show more
  • Revenue$4.02B-0.9%
  • EBITDA$911M+54.7%
  • Net Income-$144M-1501.7%
  • EPS (Diluted)-2.91-1555.0%
  • Gross Margin30.52%-7.2%
  • EBITDA Margin22.69%+56.0%
  • Operating Margin12.65%+125.3%
  • Net Margin-3.59%-1514.1%
  • ROE-4.3%-1595.4%

CRL Price & Volume

Charles River Laboratories International, Inc. (CRL) stock price & volume — 10-year historical chart

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Cyclical Headwinds Pressure Charles River Operational Margins

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Strained
Cash Flow:Deteriorating
Primary Risk:Biotech funding cycle sensitivity

Key Thesis Takeaways

  • Charles River Laboratories faces a challenging fundamental outlook characterized by stagnant revenue growth and significant margin volatility, as evidenced by the recent compression of gross margins to 28.0% in 2026Q1.
  • The company's aggressive capital allocation strategy, including $405.0 million in net acquisitions during the most recent quarter, appears to be straining the balance sheet while failing to drive consistent profitability.
  • Investors should monitor the sustainability of the current cost structure and the potential for further goodwill impairments, given that $3.0 billion in goodwill currently represents nearly 39% of total assets.

Verdict Logic

the company's inability to maintain positive net income, coupled with a volatile operating cash flow to net income ratio of -2.77, suggests significant underlying operational risks.

CRL Growth Metrics

Charles River Laboratories International, Inc. (CRL) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years11.41%
5 Years6.55%
3 Years0.33%
TTM0.11%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-485.02%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-478.46%

Return on Capital

10 Years9.7%
5 Years8.39%
3 Years6.82%
Last Year8.09%

CRL Recent Earnings

Charles River Laboratories International, Inc. (CRL) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 12/12 qtrs (100%)●Beat Revenue 12/12 qtrs (100%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$2.06+5.1%
$1.96
Rev
$996M+1.9%
$977M
Q1 2026
Feb 18, 2026
Metric
Actual
Est
EPS
$2.39+2.6%
$2.33
Rev
$994M+0.7%
$987M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$2.43+4.7%
$2.32
Rev
$1.0B+1.8%
$987M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$3.12+24.8%
$2.50
Rev
$1.0B+6.5%
$969M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$2.06vs $1.96+5.1%
$996Mvs $977M+1.9%
Q1 2026Feb 18, 2026
$2.39vs $2.33+2.6%
$994Mvs $987M+0.7%
Q4 2025Nov 5, 2025
$2.43vs $2.32+4.7%
$1.0Bvs $987M+1.8%
Q3 2025Aug 6, 2025
$3.12vs $2.50+24.8%
$1.0Bvs $969M+6.5%
Based on last 12 quarters of dataView full earnings history →

Latest CRL News

Recent stock market news and headlines for Charles River Laboratories International, Inc. (CRL)

Zacks Investment Research·6 days ago
LH or CRL: Which Is the Better Value Stock Right Now?

Investors with an interest in Medical Services stocks have likely encountered both Labcorp Holdings (LH) and Charles River Laboratories (CRL). But which of these two companies is the best option for those looking for undervalued stocks?

Zacks Investment Research·6 days ago
Is This the Right Time to Hold CRL Stock in Your Portfolio?

Charles River Laboratories International, Inc. CRL is well-poised to grow in the coming quarters owing to the strength of its Research Models and Services (“RMS”) business and broader CRADL adoption. Strategic deals continue to broaden its capabilities while streamlining its portfolio.

Seeking Alpha·Jun 23, 2026
Achieve Life Sciences: CRL Is Fixable, So I Remain Bullish

Achieve Life Sciences remains a cytisinicline story, with very positive smoking-cessation data. This also gives cytisinicline some added optionality for vaping. The FDA's CRL appears to be mostly about manufacturing and labeling issues. However, it's not about a particular cytisinicline efficacy or safety problem. ACHV is currently targeting Q4 2026 resubmission and, assuming everything goes according to plan, it could receive approval by 1H2027.

The Motley Fool·Jun 22, 2026
Bio-Rad vs. Charles River Labs: Which Medical Research Stock Is a Better Buy in 2026?

Bio-Rad Laboratories offers high profitability and a liquid balance sheet with a current ratio above 5x. Charles River Laboratories International maintains a leading scale in drug discovery services with over 19,000 employees globally.

Business Wire·Jun 18, 2026
Charles River Joins Lilly TuneLab to Optimize AI/ML Platform through Nonclinical Testing Expertise

WILMINGTON, Mass.--(BUSINESS WIRE)---- $CRL #LIFEatCRL--Charles River Laboratories International, Inc. (NYSE: CRL) announced a collaboration with Lilly TuneLab, a collaborative AI/ML drug discovery platform created by Eli Lilly and Company (Lilly). TuneLab was created to accelerate biotech innovation by enabling participating companies to access AI/ML drug discovery models trained on decades of Lilly's proprietary research data, in exchange for data contributions that improve model performance through federated le.

Peers Comparison

Key metrics vs top competitors for Charles River Laboratories International, Inc. (CRL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CRL logoCRLCharles River Laboratories International, Inc.Current
$228.68$11.01B-78.58-0.85%-3.59%-4.3%—
IQV logoIQVIQVIA Holdings Inc.
$208.23$35.34B26.565.87%8.33%22.11%—
MEDP logoMEDPMedpace Holdings, Inc.
$546.29$15.6B35.7519.97%17.19%120.89%—
ICLR logoICLRICON Public Limited Company
$168.72$12.92B58.18-0.37%5.35%4.7%—
PRA logoPRAProAssurance Corporation
$25.00$1.29B25.25-2.67%6.04%4.95%—
LBRT logoLBRTLiberty Energy Inc.
$23.66$3.83B26.58-7.16%3.71%7.39%—

Compare CRL vs Peers

Charles River Laboratories International, Inc. (CRL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IQV

Most directly comparable listed peer for CRL.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CRL against a more recognizable public peer.

Peer Set

Compare Top 5

vs IQV, MEDP, ICLR, PRA

CRL SEC Filings & Documents

Charles River Laboratories International, Inc. (CRL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 11, 2026·SEC

Material company update

May 7, 2026·SEC

Material company update

Feb 25, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 18, 2026·SEC

FY 2025

Feb 19, 2025·SEC

FY 2024

Feb 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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CRL Frequently Asked Questions

Charles River Laboratories International, Inc. (CRL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Charles River Laboratories International, Inc.'s revenue?

Charles River Laboratories International, Inc. (CRL) reported $4.03B in revenue for fiscal year 2025. This represents a 1983% increase from $193.3M in 1998.

How fast is Charles River Laboratories International, Inc. growing?

Charles River Laboratories International, Inc. (CRL) saw revenue decline by 0.9% over the past year.

Is CRL profitable?

Charles River Laboratories International, Inc. (CRL) reported a net loss of $184.7M for fiscal year 2025.

Dividend & Returns
What is CRL's return on equity?

Charles River Laboratories International, Inc. (CRL) has a return on equity (ROE) of -4.3%. Negative ROE indicates the company is unprofitable.

What is Charles River Laboratories International, Inc.'s free cash flow?

Charles River Laboratories International, Inc. (CRL) generated $391.3M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in CRL back in 1998?

Total return calculator · dividends reinvested · 28+ years of data

See returns →