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CRISCuris, Inc.
$5.94$12M
Overview & Verdict
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CRIS logoCuris, Inc.(CRIS)Earnings, Financials & Key Ratios

CRIS•NASDAQ
$5.94
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutCuris, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small molecule drug candidate, which is in a Phase 1/2 clinical trial for the treatment of non-hodgkin lymphomas, and acute myeloid leukemia and myelodysplastic syndromes; and CI-8993, a monoclonal antibody designed to antagonize the V-domain Ig suppressor of T cell activation. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with MYC-altered diffuse large B-cell lymphoma; CA-170, an oral small molecule drug candidate for treating patients with advanced solid tumors and lymphomas; and CA-327, a pre-investigational new drug stage oncology drug candidate. It has collaboration agreement with F. Hoffmann-La Roche Ltd. and Genentech Inc. for the development and commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway inhibitor for the treatment of advanced basal cell carcinoma; and with Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.Show more
  • Revenue$9M-13.4%
  • EBITDA-$33M+26.2%
  • Net Income-$8M+82.5%
  • EPS (Diluted)-11.60+91.6%
  • Gross Margin99.52%+0.4%
  • EBITDA Margin-346.64%+14.7%
  • Operating Margin-348.43%+14.7%
  • Net Margin-80.29%+79.8%
  • ROE-138.81%+78.1%

CRIS Price & Volume

Curis, Inc. (CRIS) stock price & volume — 10-year historical chart

Loading chart...

Structural Revenue Collapse Threatens Clinical Pipeline Viability

Investment Thesis • Updated 2026Q1

VerdictNegative: The company's liquidity position is severely constrained
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity exhaustion

Key Thesis Takeaways

  • Curis faces an existential financial crisis characterized by the total erosion of its legacy royalty revenue stream and a persistent, high-burn R&D model.
  • The company's reliance on external financing to sustain operations is increasingly precarious, as evidenced by a decade of accumulated losses totaling approximately -$1.2B in retained earnings.
  • Investors should remain cautious as the firm's inability to achieve operating leverage, combined with a current ratio of 1.00 as of 2026Q1, suggests a high probability of further dilutive capital raises or potential insolvency.

Verdict Logic

with cash reserves of only $15.0M as of 2026Q1 and a history of quarterly operating losses that frequently exceed $10M, signaling an imminent risk of further shareholder dilution.

CRIS Growth Metrics

Curis, Inc. (CRIS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years1.83%
5 Years-2.71%
3 Years-2.42%
TTM-36.95%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM49.76%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM80.9%

Return on Capital

10 Years-82.35%
5 Years-95.79%
3 Years-137.21%
Last Year-233.94%

CRIS Recent Earnings

Curis, Inc. (CRIS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 4/12 qtrs (36%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$1.25-331.0%
$0.29
Rev
—
$2M
Q2 2026
Mar 19, 2026
Metric
Actual
Est
EPS
$0.50-14.7%
$0.44
Rev
$1M-65.0%
$3M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.49+21.0%
$0.62
Rev
$3M+11.0%
$3M
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$0.68+65.8%
$1.99
Rev
$3M-3.9%
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$1.25vs $0.29-331.0%
—vs $2M
Q2 2026Mar 19, 2026
$0.50vs $0.44-14.7%
$1Mvs $3M-65.0%
Q4 2025Nov 6, 2025
$0.49vs $0.62+21.0%
$3Mvs $3M+11.0%
Q3 2025Aug 5, 2025
$0.68vs $1.99+65.8%
$3Mvs $3M-3.9%
Based on last 12 quarters of dataView full earnings history →

Latest CRIS News

Recent stock market news and headlines for Curis, Inc. (CRIS)

GuruFocus·Jun 26, 2026
Curis Announces Eleven Active Clinical Sites in TakeAim CLL Study, Reaffirms Patient Dosing Guidance, and Reports Stockholder Approval of Reverse Stock Split

Curis Announces Eleven Active Clinical Sites in TakeAim CLL Study, Reaffirms Patient Dosing Guidance, and Reports Stockholder Approval of Rever

PRNewsWire·Jun 26, 2026
Curis Announces Eleven Active Clinical Sites in TakeAim CLL Study, Reaffirms Patient Dosing Guidance, and Reports Stockholder Approval of Reverse Stock Split

Eleven sites open for patient enrollment in TakeAim CLL combination study with zanubrutinib; Company reaffirms guidance for dosing of initial five patients by end of July 2026 with data expected December 2026; Stockholders approve reverse stock split LEXINGTON, Mass., June 26, 2026 /PRNewswire/ -- Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of emavusertib (CA-4948), an orally available, small molecule IRAK4 and FLT3 inhibitor, today announced that eleven clinical sites have been initiated and are now open for patient enrollment in its Phase 2 TakeAim CLL study evaluating emavusertib in combination with zanubrutinib in patients with Chronic Lymphocytic Leukemia.

Peers Comparison

Key metrics vs top competitors for Curis, Inc. (CRIS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CRIS logoCRISCuris, Inc.Current
$5.94$11.58M-0.51-13.43%-80.29%-138.81%—
TGTX logoTGTXTG Therapeutics, Inc.
$53.52$8.19B19.3287.32%65.95%87.36%—
KPTI logoKPTIKaryopharm Therapeutics Inc.
$9.62$82.13M-0.540.57%-129.02%——
MGNX logoMGNXMacroGenics, Inc.
$4.57$290.48M-3.870.78%-44.79%-147.8%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
PRTA logoPRTAProthena Corporation plc
$9.50$497.36M-2.10-92.84%-260.92%-49.88%—

Compare CRIS vs Peers

Curis, Inc. (CRIS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs TGTX

Most directly comparable listed peer for CRIS.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare CRIS against a more recognizable public peer.

Peer Set

Compare Top 5

vs TGTX, KPTI, MGNX, IMVT

CRIS SEC Filings & Documents

Curis, Inc. (CRIS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

May 1, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 24, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Feb 8, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 5, 2025·SEC

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CRIS Frequently Asked Questions

Curis, Inc. (CRIS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Curis, Inc.'s revenue?

Curis, Inc. (CRIS) reported $7.1M in revenue for fiscal year 2025. This represents a 120% increase from $3.2M in 1999.

How fast is Curis, Inc. growing?

Curis, Inc. (CRIS) saw revenue decline by 13.4% over the past year.

Is CRIS profitable?

Curis, Inc. (CRIS) reported a net loss of $21.2M for fiscal year 2025.

Dividend & Returns
What is CRIS's return on equity?

Curis, Inc. (CRIS) has a return on equity (ROE) of -138.8%. Negative ROE indicates the company is unprofitable.

What is Curis, Inc.'s free cash flow?

Curis, Inc. (CRIS) had negative free cash flow of $28.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CRIS back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

See returns →