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CRDFCardiff Oncology, Inc.
$1.30$89M
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CRDF logoCardiff Oncology, Inc.(CRDF)Earnings, Financials & Key Ratios

CRDF•NASDAQ
$1.30
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutCardiff Oncology, Inc., a clinical-stage oncology company, develops medicine treatment for cancer patients in California. Its lead drug candidate is onvansertib, an oral selective Polo-like Kinase 1 Inhibitor for anti-cancer therapeutics; CY140, an inhibitor of PLK1, PLK2, and PLK3 that is in phase 1/2 studies in solid tumors and leukemias; metastatic colorectal cancer that is in clinical trials; and TROV-054 is a Phase 1b/2 for FOLFIRI and bevacizumab. The company's TROV-053 is also in Phase II clinical trial in combination with Zytiga for metastatic castration-resistant prostate cancer. The company primarily serves pharmaceutical manufacturers. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was incorporated in 1999 and is headquartered in San Diego, California.Show more
  • Revenue$593K-13.2%
  • EBITDA-$48M+0.4%
  • Net Income-$46M-0.9%
  • EPS (Diluted)-0.69+27.4%
  • Gross Margin100%
  • EBITDA Margin-8103.88%-14.7%
  • Operating Margin-8256.32%-15.9%
  • Net Margin-7732.04%-16.2%
  • ROE-71.45%-20.1%

CRDF Price & Volume

Cardiff Oncology, Inc. (CRDF) stock price & volume — 10-year historical chart

Loading chart...

Persistent Clinical Burn Challenges Cardiff Oncology Solvency

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding insolvency

Key Thesis Takeaways

  • Cardiff Oncology remains a high-risk, pre-commercial biotechnology firm characterized by a lack of sustainable revenue and a heavy reliance on equity-based financing to fund its clinical pipeline.
  • The company's financial trajectory is defined by deep operating losses, with R&D expenditures of $6.8 million in 2026Q1 consistently outpacing its minimal $41,000 revenue base.
  • Investors should monitor the rapidly depleting cash position, which fell to $8.5 million in 2026Q1, as the firm faces significant liquidity constraints that may necessitate further dilutive capital raises.

Verdict Logic

the company's cash runway is critically low at $8.5 million against a quarterly operating loss of $12.8 million, signaling an urgent need for dilutive financing.

CRDF Growth Metrics

Cardiff Oncology, Inc. (CRDF) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years6.6%
5 Years10.13%
3 Years15.39%
TTM-10.71%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM8.36%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM35.58%

Return on Capital

10 Years-81.13%
5 Years-48.42%
3 Years-63.04%
Last Year-75.76%

CRDF Recent Earnings

Cardiff Oncology, Inc. (CRDF) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 11/12 qtrs (92%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.18-38.5%
$0.13
Rev
$41,000-53.7%
$88,571
Q1 2026
Feb 24, 2026
Metric
Actual
Est
EPS
$0.11+38.9%
$0.18
Rev
$243,000+134.8%
$103,500
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.17+15.0%
$0.20
Rev
$120,000+15.9%
$103,500
Q3 2025
Jul 29, 2025
Metric
Actual
Est
EPS
$0.21-10.5%
$0.19
Rev
$121,000+10.6%
$109,375
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.18vs $0.13-38.5%
$41,000vs $88,571-53.7%
Q1 2026Feb 24, 2026
$0.11vs $0.18+38.9%
$243,000vs $103,500+134.8%
Q4 2025Nov 6, 2025
$0.17vs $0.20+15.0%
$120,000vs $103,500+15.9%
Q3 2025Jul 29, 2025
$0.21vs $0.19-10.5%
$121,000vs $109,375+10.6%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Cardiff Oncology, Inc. (CRDF)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CRDF logoCRDFCardiff Oncology, Inc.Current
$1.30$88.88M-1.88-13.18%-7732.04%-71.45%—
TGTX logoTGTXTG Therapeutics, Inc.
$53.52$8.19B19.3287.32%65.95%87.36%—
MGNX logoMGNXMacroGenics, Inc.
$4.57$290.48M-3.870.78%-44.79%-147.8%—
NKTR logoNKTRNektar Therapeutics
$73.15$1.43B-7.52-43.89%-284.18%-87%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
KPTI logoKPTIKaryopharm Therapeutics Inc.
$9.62$82.13M-0.540.57%-129.02%——

Compare CRDF vs Peers

Cardiff Oncology, Inc. (CRDF) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs TGTX

Most directly comparable listed peer for CRDF.

Scale Benchmark

vs RVMD

Larger-name benchmark to compare CRDF against a more recognizable public peer.

Peer Set

Compare Top 5

vs TGTX, MGNX, NKTR, IMVT

CRDF SEC Filings & Documents

Cardiff Oncology, Inc. (CRDF) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 19, 2026·SEC

Material company update

May 14, 2026·SEC

Material company update

Apr 9, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Jul 29, 2025·SEC

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CRDF Frequently Asked Questions

Cardiff Oncology, Inc. (CRDF) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Cardiff Oncology, Inc.'s revenue?

Cardiff Oncology, Inc. (CRDF) reported $0.5M in revenue for fiscal year 2025.

How fast is Cardiff Oncology, Inc. growing?

Cardiff Oncology, Inc. (CRDF) saw revenue decline by 13.2% over the past year.

Is CRDF profitable?

Cardiff Oncology, Inc. (CRDF) reported a net loss of $44.8M for fiscal year 2025.

Dividend & Returns
What is CRDF's return on equity?

Cardiff Oncology, Inc. (CRDF) has a return on equity (ROE) of -71.5%. Negative ROE indicates the company is unprofitable.

What is Cardiff Oncology, Inc.'s free cash flow?

Cardiff Oncology, Inc. (CRDF) had negative free cash flow of $37.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CRDF back in 2005?

Total return calculator · dividends reinvested · 21+ years of data

See returns →