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CRBUCaribou Biosciences, Inc.
$1.92$190M
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CRBU logoCaribou Biosciences, Inc.(CRBU)Earnings, Financials & Key Ratios

CRBU•NASDAQ
$1.92
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutCaribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.Show more
  • Revenue$11M+11.7%
  • EBITDA-$133M+18.5%
  • Net Income-$148M+0.7%
  • EPS (Diluted)-1.59+3.6%
  • Gross Margin67.34%+10.9%
  • EBITDA Margin-1187.82%+27.0%
  • Operating Margin-1220.49%+26.8%
  • Net Margin-1327.4%+11.0%
  • ROE-78.97%-64.5%

CRBU Price & Volume

Caribou Biosciences, Inc. (CRBU) stock price & volume — 10-year historical chart

Loading chart...

Persistent Clinical Burn Threatens Capital Runway Stability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity shortfall

Key Thesis Takeaways

  • Caribou Biosciences faces a critical liquidity inflection point as its chRDNA platform development continues to outpace its ability to generate sustainable, non-milestone-dependent revenue.
  • While the company maintains a low debt-to-equity ratio of 0.26, the rapid erosion of its cash position from $51.2 million in 2023Q4 to $12.1 million in 2026Q1 suggests an imminent need for dilutive financing.
  • Investors should monitor the company's ability to secure strategic partnerships, as current operating losses of $26.3 million per quarter remain fundamentally incompatible with its existing cash reserves.

Verdict Logic

the company's current cash balance of $12.1 million against a quarterly operating loss of $26.3 million suggests an imminent liquidity shortfall that warrants extreme caution.

CRBU Growth Metrics

Caribou Biosciences, Inc. (CRBU) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-2.03%
3 Years-6.95%
TTM12.96%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM9.9%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM12.35%

Return on Capital

10 Years-51.81%
5 Years-40.16%
3 Years-47.49%
Last Year-62.96%

CRBU Recent Earnings

Caribou Biosciences, Inc. (CRBU) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 9/12 qtrs (75%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.26+21.2%
$0.33
Rev
$2M+8.3%
$2M
Q2 2026
Mar 5, 2026
Metric
Actual
Est
EPS
$0.28+15.2%
$0.33
Rev
$4M+78.6%
$2M
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.30+16.7%
$0.36
Rev
$2M+12.3%
$2M
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.35+12.5%
$0.40
Rev
$3M+74.1%
$2M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.26vs $0.33+21.2%
$2Mvs $2M+8.3%
Q2 2026Mar 5, 2026
$0.28vs $0.33+15.2%
$4Mvs $2M+78.6%
Q4 2025Nov 12, 2025
$0.30vs $0.36+16.7%
$2Mvs $2M+12.3%
Q3 2025Aug 12, 2025
$0.35vs $0.40+12.5%
$3Mvs $2M+74.1%
Based on last 12 quarters of dataView full earnings history →

Latest CRBU News

Recent stock market news and headlines for Caribou Biosciences, Inc. (CRBU)

GlobeNewsWire·Jun 29, 2026
Caribou Biosciences to Participate in the H.C. Wainwright 4th Annual Cell Therapy Virtual Conference

BERKELEY, Calif., June 29, 2026 (GLOBE NEWSWIRE) -- Caribou Biosciences, Inc. (Nasdaq: CRBU), a leading clinical-stage CRISPR genome-editing biopharmaceutical company, today announced Rachel Haurwitz, PhD, Caribou's president and chief executive officer, will participate in a fireside chat at the H.C.

Peers Comparison

Key metrics vs top competitors for Caribou Biosciences, Inc. (CRBU)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CRBU logoCRBUCaribou Biosciences, Inc.Current
$1.92$190.43M-1.2111.66%-1327.4%-78.97%—
EDIT logoEDITEditas Medicine, Inc.
$3.75$367.15M-2.0825.39%-281.59%-677.39%—
BEAM logoBEAMBeam Therapeutics Inc.
$37.92$3.9B-46.81120.01%-49.17%-5.89%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$17.43$1.96B-4.5716.92%-597.04%-57.27%—
CRSP logoCRSPCRISPR Therapeutics AG
$60.77$5.86B-9.39-89.97%-13856.54%-30.88%—
FATE logoFATEFate Therapeutics, Inc.
$3.02$352.01M-2.63-51.24%-2056.79%-58.89%—

Compare CRBU vs Peers

Caribou Biosciences, Inc. (CRBU) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs EDIT

Most directly comparable listed peer for CRBU.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CRBU against a more recognizable public peer.

Peer Set

Compare Top 5

vs EDIT, BEAM, NTLA, CRSP

CRBU SEC Filings & Documents

Caribou Biosciences, Inc. (CRBU) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Mar 31, 2026·SEC

Material company update

Mar 5, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 5, 2026·SEC

FY 2025

Mar 10, 2025·SEC

FY 2024

Mar 11, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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CRBU Frequently Asked Questions

Caribou Biosciences, Inc. (CRBU) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Caribou Biosciences, Inc.'s revenue?

Caribou Biosciences, Inc. (CRBU) reported $11.2M in revenue for fiscal year 2025. This represents a 94% increase from $5.8M in 2019.

How fast is Caribou Biosciences, Inc. growing?

Caribou Biosciences, Inc. (CRBU) grew revenue by 11.7% over the past year. This is steady growth.

Is CRBU profitable?

Caribou Biosciences, Inc. (CRBU) reported a net loss of $133.2M for fiscal year 2025.

Dividend & Returns
What is CRBU's return on equity?

Caribou Biosciences, Inc. (CRBU) has a return on equity (ROE) of -79.0%. Negative ROE indicates the company is unprofitable.

What is Caribou Biosciences, Inc.'s free cash flow?

Caribou Biosciences, Inc. (CRBU) had negative free cash flow of $101.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CRBU back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →