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ALMSAlumis Inc. Common Stock
$27.27$3.4B
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ALMS logoAlumis Inc. Common Stock(ALMS)Earnings, Financials & Key Ratios

ALMS•NASDAQ
$27.27
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutAlumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. It develops ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.Show more
  • Revenue$24M
  • EBITDA-$424M-42.4%
  • Net Income-$243M+17.3%
  • EPS (Diluted)-2.86+72.4%
  • Gross Margin85.46%
  • EBITDA Margin-1761.78%
  • Operating Margin-1776.32%
  • Net Margin-1011.75%
  • ROE-86.69%+23.4%

ALMS Price & Volume

Alumis Inc. Common Stock (ALMS) stock price & volume — 10-year historical chart

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Clinical Development Costs Outpace Revenue Milestone Potential

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent clinical funding gap

Key Thesis Takeaways

  • Alumis faces a precarious financial outlook as its reliance on erratic milestone payments, which plummeted to $1.7 million in 2026Q1, fails to offset the massive R&D expenditures that reached $108.8 million in 2025Q2.
  • The company's structural dependence on external funding is underscored by a $994.9 million accumulated deficit, which severely impairs equity quality and limits strategic flexibility.
  • Investors should monitor the rapid depletion of cash reserves, which fell from $213.4 million in 2024Q3 to $63.9 million in 2026Q1, as the firm struggles to sustain its late-stage clinical pipeline.

Verdict Logic

the company's cash position has contracted to $63.9 million as of 2026Q1, which appears insufficient to support the ongoing, high-intensity R&D requirements that previously demanded over $100 million in quarterly spending.

ALMS Growth Metrics

Alumis Inc. Common Stock (ALMS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-51.68%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM30.85%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM69.67%

Return on Capital

10 Years-154.26%
5 Years-154.26%
3 Years-165.65%
Last Year-135.9%

ALMS Recent Earnings

Alumis Inc. Common Stock (ALMS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (38%)●Beat Revenue 2/12 qtrs (33%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.74+0.4%
$0.74
Rev
$2M-15.4%
$2M
Q2 2026
Mar 19, 2026
Metric
Actual
Est
EPS
$0.95+2.1%
$0.97
Rev
$2M-18.4%
$2M
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$1.06-15.2%
$0.92
Rev
$2M-24.9%
$3M
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$1.17-5.4%
$1.11
Rev
$3M-15.2%
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.74vs $0.74+0.4%
$2Mvs $2M-15.4%
Q2 2026Mar 19, 2026
$0.95vs $0.97+2.1%
$2Mvs $2M-18.4%
Q4 2025Nov 13, 2025
$1.06vs $0.92-15.2%
$2Mvs $3M-24.9%
Q3 2025Aug 13, 2025
$1.17vs $1.11-5.4%
$3Mvs $3M-15.2%
Based on last 12 quarters of dataView full earnings history →

Latest ALMS News

Recent stock market news and headlines for Alumis Inc. Common Stock (ALMS)

Seeking Alpha·Jun 25, 2026
Alumis: Is Envudeucitinib The 'Real Deal?' We Should Find Out Soon

Alumis receives a renewed Buy rating, driven by upcoming data catalysts for lead candidate envudeucitinib in psoriasis and SLE. Phase 3 data for envudeucitinib showed strong efficacy and safety, though not outright superiority versus competitors, and twice-daily dosing is a minor drawback. Upcoming 2026 catalysts include long-term psoriasis data, NDA submission, and pivotal SLE data, all critical for valuation and acquisition potential.

Peers Comparison

Key metrics vs top competitors for Alumis Inc. Common Stock (ALMS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ALMS logoALMSAlumis Inc. Common StockCurrent
$27.27$3.41B-9.54—-1011.75%-86.69%—
ABBV logoABBVAbbVie Inc.
$254.76$450.11B107.498.57%5.79%67.46%—
CLDX logoCLDXCelldex Therapeutics, Inc.
$37.95$2.53B-9.73-78.63%-34596.22%-50.72%—
ARVN logoARVNArvinas, Inc.
$8.45$545.2M-6.60-0.3%-247.54%-44.39%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
VTRS logoVTRSViatris Inc.
$16.80$19.56B-5.60-2.98%-2.04%-1.97%—

Compare ALMS vs Peers

Alumis Inc. Common Stock (ALMS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ABBV

Most directly comparable listed peer for ALMS.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare ALMS against a more recognizable public peer.

Peer Set

Compare Top 5

vs ABBV, CLDX, ARVN, IMVT

ALMS SEC Filings & Documents

Alumis Inc. Common Stock (ALMS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 14, 2026·SEC

Material company update

Mar 30, 2026·SEC

Material company update

Mar 19, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 19, 2026·SEC

FY 2025

Mar 19, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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ALMS Frequently Asked Questions

Alumis Inc. Common Stock (ALMS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Alumis Inc. Common Stock's revenue?

Alumis Inc. Common Stock (ALMS) reported $8.4M in revenue for fiscal year 2025.

Is ALMS profitable?

Alumis Inc. Common Stock (ALMS) reported a net loss of $237.4M for fiscal year 2025.

Dividend & Returns
What is ALMS's return on equity?

Alumis Inc. Common Stock (ALMS) has a return on equity (ROE) of -86.7%. Negative ROE indicates the company is unprofitable.

What is Alumis Inc. Common Stock's free cash flow?

Alumis Inc. Common Stock (ALMS) had negative free cash flow of $377.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ALMS back in 2022?

Total return calculator · dividends reinvested · 4+ years of data

See returns →