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ACADACADIA Pharmaceuticals Inc.
$26.20$4.5B
Overview & Verdict
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ACAD logoACADIA Pharmaceuticals Inc.(ACAD)Earnings, Financials & Key Ratios

ACAD•NASDAQ
$26.20
11.4× P/E·Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of small molecule drugs that address unmet medical needs in central nervous system disorders. The company offers NUPLAZID (pimavanserin) for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. It's pipeline include, pimavanserin, under phase 3 development for the treatment of Alzheimer's disease psychosis, and negative symptoms of schizophrenia; Trofinetide, a novel synthetic analog, under phase 3 development for the treatment of Rett syndrome; ACP-044, a novel first-in-class orally administered non-opioid analgesic, under phase 2 development for treating acute and chronic pain; and ACP-319, a positive allosteric modulator of the muscarinic receptor, under phase 1 development for treating schizophrenia and cognition in Alzheimer's. ACADIA Pharmaceuticals Inc. was founded in 1993 and is headquartered in San Diego, California.Show more
  • Revenue$1.07B+11.9%
  • EBITDA$139M-43.7%
  • Net Income$391M+72.7%
  • EPS (Diluted)2.29+68.4%
  • Gross Margin91.69%+0.3%
  • EBITDA Margin12.96%-49.7%
  • Operating Margin9.78%-59.4%
  • Net Margin36.49%+54.3%
  • ROE39.89%+2.6%

ACAD Price & Volume

ACADIA Pharmaceuticals Inc. (ACAD) stock price & volume — 10-year historical chart

Loading chart...

Commercial Maturation Challenges Amidst Operating Margin Compression

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Decelerating
Profitability:Moderate
Financial:Healthy
Cash Flow:Mixed
Primary Risk:Pipeline concentration and regulatory

Key Thesis Takeaways

  • ACADIA Pharmaceuticals is transitioning from a high-growth launch phase to a more mature commercial stage, as evidenced by revenue growth decelerating to 9.7% in 2026Q1.
  • While the company maintains a robust gross margin profile consistently above 90%, the heavy reliance on SG&A spending to support its CNS portfolio has pressured operating margins into negative territory at -1.7%.
  • Investors should monitor the company's ability to achieve sustainable operating leverage and reconcile its volatile cash flow conversion, which currently shows a wide range of operating cash flow to net income ratios.

Verdict Logic

while the balance sheet is healthy with $851.5 million in cash, the deceleration in revenue growth to 9.7% and inconsistent cash conversion warrant a cautious wait-and-see approach.

ACAD Growth Metrics

ACADIA Pharmaceuticals Inc. (ACAD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years165.75%
5 Years19.39%
3 Years27.48%
TTM9.93%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM64.12%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM60.58%

Return on Capital

10 Years-32.59%
5 Years-7.59%
3 Years10.2%
Last Year10.08%

ACAD Recent Earnings

ACADIA Pharmaceuticals Inc. (ACAD) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 10/12 qtrs (83%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$0.02-50.0%
$0.04
Rev
$268M-4.3%
$280M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$1.60+1067.9%
$0.14
Rev
$284M-3.0%
$293M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.26+85.7%
$0.14
Rev
$279M-4.8%
$293M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.16+14.3%
$0.14
Rev
$265M+1.0%
$262M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$0.02vs $0.04-50.0%
$268Mvs $280M-4.3%
Q1 2026Feb 25, 2026
$1.60vs $0.14+1067.9%
$284Mvs $293M-3.0%
Q4 2025Nov 5, 2025
$0.26vs $0.14+85.7%
$279Mvs $293M-4.8%
Q3 2025Aug 6, 2025
$0.16vs $0.14+14.3%
$265Mvs $262M+1.0%
Based on last 12 quarters of dataView full earnings history →

Latest ACAD News

Recent stock market news and headlines for ACADIA Pharmaceuticals Inc. (ACAD)

Zacks Investment Research·Jun 29, 2026
ACAD Stock Up as CHMP Backs Daybu for EU Approval in Rett Syndrome

Acadia stock jumps 7% as CHMP backs Daybu for EU approval in Rett syndrome, with the European Commission set to make a final decision in the coming months.

Seeking Alpha·Jun 29, 2026
Acadia Pharmaceuticals: Steady Commercial Progress, Remlifanserin Data In Focus

Acadia Pharmaceuticals demonstrates steady commercial growth with Nuplazid and Daybue, supported by a recent positive CHMP opinion for Daybue in Europe. Remlifanserin's upcoming phase 2 readout in Alzheimer's disease psychosis is a high-risk, high-reward catalyst not priced into ACAD's current valuation. I maintain a bullish outlook on ACAD based on commercial products Nuplazid and Daybue, but above-average returns depend on pipeline or business development success.

Zacks Investment Research·Jun 29, 2026
Strength Seen in Acadia (ACAD): Can Its 6.8% Jump Turn into More Strength?

Acadia (ACAD) was a big mover last session on higher-than-average trading volume. The latest trend in earnings estimate revisions might not help the stock continue moving higher in the near term.

Benzinga·Jun 26, 2026
Acadia Pharma Stock Jumps After European Panel Reverses Course On Rett Syndrome Therapy

Acadia Pharmaceuticals Inc. (NASDAQ:ACAD) shares are trading higher on Friday as the company is celebrating a positive recommendation from the European Medicines Agency Committee for Medicinal Products for Human Use (CHMP) regarding its drug DAYBU (trofinetide) for treating neurobehavioral symptoms of Rett syndrome in the European Union.

The Motley Fool·Jun 26, 2026
Why Acadia Pharmaceuticals Stock Is Soaring Today

Acadia Pharmaceuticals focuses on underserved rare diseases. Although they're (by definition) small markets, there's often little to no competition to treat rare and underserved diseases.

Peers Comparison

Key metrics vs top competitors for ACADIA Pharmaceuticals Inc. (ACAD)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ACAD logoACADACADIA Pharmaceuticals Inc.Current
$26.20$4.49B11.4411.87%36.49%39.89%—
INVA logoINVAInnoviva, Inc.
$22.25$1.64B6.7418.52%118.91%47.59%—
AXSM logoAXSMAxsome Therapeutics, Inc.
$249.76$12.85B-67.8765.55%-26.59%-260.01%—
INTR logoINTRInter & Co, Inc.
$5.59$2.47B9.9050.54%8.99%14.24%—
PTCT logoPTCTPTC Therapeutics, Inc.
$89.20$7.4B11.47114.51%-22.58%——
BIIB logoBIIBBiogen Inc.
$205.70$30.37B23.301.39%13.92%7.55%—

Compare ACAD vs Peers

ACADIA Pharmaceuticals Inc. (ACAD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs INVA

Most directly comparable listed peer for ACAD.

Scale Benchmark

vs CVS

Larger-name benchmark to compare ACAD against a more recognizable public peer.

Peer Set

Compare Top 5

vs INVA, AXSM, INTR, PTCT

ACAD SEC Filings & Documents

ACADIA Pharmaceuticals Inc. (ACAD) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Mar 5, 2026·SEC

Material company update

Feb 25, 2026·SEC

10-K Annual Reports

2
FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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ACAD Frequently Asked Questions

ACADIA Pharmaceuticals Inc. (ACAD) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is ACADIA Pharmaceuticals Inc.'s revenue?

ACADIA Pharmaceuticals Inc. (ACAD) reported $1.10B in revenue for fiscal year 2025. This represents a 25300% increase from $4.3M in 2000.

How fast is ACADIA Pharmaceuticals Inc. growing?

ACADIA Pharmaceuticals Inc. (ACAD) grew revenue by 11.9% over the past year. This is steady growth.

Is ACAD profitable?

Yes, ACADIA Pharmaceuticals Inc. (ACAD) is profitable, generating $375.6M in net income for fiscal year 2025 (36.5% net margin).

Dividend & Returns
What is ACAD's return on equity?

ACADIA Pharmaceuticals Inc. (ACAD) has a return on equity (ROE) of 39.9%. This is excellent, indicating efficient use of shareholder capital.

What is ACADIA Pharmaceuticals Inc.'s free cash flow?

ACADIA Pharmaceuticals Inc. (ACAD) generated $212.4M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in ACAD back in 2000?

Total return calculator · dividends reinvested · 26+ years of data

See returns →